Results 121 to 130 of about 191,697 (275)
Human memory Th cells were separated into Tcm (CD45RO+ CD62L+) and Tem (CD45RO+ CD62L−). Nicotine preferentially suppressed Th1‐, Th2‐, Th17‐, and Tfh‐associated programs in Tcm via an α7nAChR‐dependent mechanism, with minimal effect in Tem. ABSTRACT Memory T helper (Th) cells sustain protective recall responses but can also drive chronic inflammation,
Fatemeh Gholizadeh +10 more
wiley +1 more source
The Glymphatic System and Meningeal Lymphatics: Current Understandings and Future Perspectives
Brain waste clearance relies on the anatomical and functional integration of the glymphatic system and meningeal lymphatic vessels. Cerebrospinal fluid influx into the brain parenchyma occurs along periarterial spaces, a process driven by polarized aquaporin‐4 (AQP4) water channels on astrocytic endfeet.
Hangzhe Sun +8 more
wiley +1 more source
Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei +4 more
wiley +1 more source
Current treatments for autoimmune diseases often involve broad‐acting immunosuppressants, which carry risks such as infections and malignancies. This study investigates whether exosomes derived from anti‐inflammatory macrophages (AE) and decorated with ...
Qiaoyun Li +5 more
doaj +1 more source
431. CCR5-Transduced Neural Stem Cells Confer Accelerated and Enhanced Therapeutic Effect on Experimental Autoimmune Encephalomyelitis [PDF]
openalex +1 more source
This review synthesizes current mechanistic and clinical evidence on IL‐6 inhibitors, particularly sarilumab and tocilizumab, concerning their effect on pain in RA. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune systemic disease in which pain remains a major and often refractory symptom even after clinical remission of the disease.
Andrej Belančić +10 more
wiley +1 more source
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si +4 more
wiley +1 more source

