Results 121 to 130 of about 191,697 (275)

Nicotine Suppresses Human Memory Th Cell Subsets With Preferential Effects on Central Memory Th Cells in an α7 Nicotinic Acetylcholine Receptor‐Dependent Manner

open access: yesEuropean Journal of Immunology, Volume 56, Issue 4, April 2026.
Human memory Th cells were separated into Tcm (CD45RO+ CD62L+) and Tem (CD45RO+ CD62L−). Nicotine preferentially suppressed Th1‐, Th2‐, Th17‐, and Tfh‐associated programs in Tcm via an α7nAChR‐dependent mechanism, with minimal effect in Tem. ABSTRACT Memory T helper (Th) cells sustain protective recall responses but can also drive chronic inflammation,
Fatemeh Gholizadeh   +10 more
wiley   +1 more source

Author response for "<i>Dicrocoelium</i> Ova Can Block the Induction Phase of Experimental Autoimmune Encephalomyelitis"

open access: gold, 2020
Zahra Navi   +9 more
openalex   +1 more source

The Glymphatic System and Meningeal Lymphatics: Current Understandings and Future Perspectives

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Brain waste clearance relies on the anatomical and functional integration of the glymphatic system and meningeal lymphatic vessels. Cerebrospinal fluid influx into the brain parenchyma occurs along periarterial spaces, a process driven by polarized aquaporin‐4 (AQP4) water channels on astrocytic endfeet.
Hangzhe Sun   +8 more
wiley   +1 more source

Lingual Dyskinesia as the Presenting Feature of Acquired Demyelinating Syndrome: A Case Report and Review of Differential Diagnoses

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Briana Davis   +3 more
wiley   +1 more source

Modulatory Effects of Folic Acid and Dental Pulp Stem Cell‐Derived Exosomes on Gene Expression in a Periodontal Injury Model

open access: yesNatural Sciences, Volume 6, Issue 2, April 2026.
Dental pulp stem cellderived exosomes and folic acid are evaluated for their effects on gene expression in an in‐vitro periodontal injury model. Human gingival fibroblasts subjected to oxidative and mechanical injury are treated with folic acid, exosomes, or their combination.
Saghar Zarei   +4 more
wiley   +1 more source

Anti‐Inflammatory Macrophage‐Derived Exosomes Modified With Self‐Antigen Peptides for Treatment of Experimental Autoimmune Encephalomyelitis

open access: yesAdvanced Science
Current treatments for autoimmune diseases often involve broad‐acting immunosuppressants, which carry risks such as infections and malignancies. This study investigates whether exosomes derived from anti‐inflammatory macrophages (AE) and decorated with ...
Qiaoyun Li   +5 more
doaj   +1 more source

Effect of Interleukin‐6 Inhibitors on Rheumatoid Arthritis Pain: Overview of Evidence and Mechanistic Pathways

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
This review synthesizes current mechanistic and clinical evidence on IL‐6 inhibitors, particularly sarilumab and tocilizumab, concerning their effect on pain in RA. ABSTRACT Rheumatoid arthritis (RA) is an autoimmune systemic disease in which pain remains a major and often refractory symptom even after clinical remission of the disease.
Andrej Belančić   +10 more
wiley   +1 more source

MyD88 Deficiency Protects Mice From Experimental Autoimmune Encephalomyelitis by Influencing Both Dendritic Cells and T Cells

open access: yesImmunology, Volume 177, Issue 4, Page 784-797, April 2026.
This study investigates the role of MyD88 in dendritic cells (DCs) and T cells during experimental autoimmune encephalomyelitis (EAE). We found that MyD88 is highly expressed in DCs and CD4+ T cells in people with multiple sclerosis, and its deficiency impairs DC maturation, reduces pro‐inflammatory cytokine production, weakens DC–T cell interactions ...
Wen Si   +4 more
wiley   +1 more source

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