Results 121 to 130 of about 132,871 (277)

Nanoparticles in Vascular Dementia: Advantages and Challenges

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This review highlights the dual diagnostic and therapeutic potential of nanomaterials in Vascular Dementia (VaD). By effectively crossing the blood–brain barrier, functionalized nanoparticles facilitate early diagnosis by targeting Aβ deposits and vascular lesions.
Xianxin Liu   +8 more
wiley   +1 more source

Measuring Calcium Efflux in Isolated Primary Mitochondria

open access: yesCurrent Protocols, Volume 6, Issue 6, June 2026.
Abstract Mitochondrial calcium (mCa2+) homeostasis promotes oxidative metabolism within the physiological range; however, dysregulation can trigger necrotic cell death in diseases such as cardiac ischemia‐reperfusion injury, muscular dystrophy, and neurodegenerative disorders, including Alzheimer's disease.
Ta'Aliyah M. Jones   +2 more
wiley   +1 more source

Physiology, pathology and therapeutic potential of microglial triggering receptor expressed on myeloid cells 2 signalling: A narrative update

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
TREM2hi microglia and macrophages exert distinct roles in neurological diseases. Enhancing TREM2 signalling supports pathological protein or debris clearance and mitigates inflammation in Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, demyelination disorders and stroke, whereas blocking TREM2 may alleviate tauopathy and ...
Zhe Kong   +3 more
wiley   +1 more source

Isolated bilateral optic neuritis in acute disseminated encephalomyelitis [PDF]

open access: bronze, 2006
Regitze Bangsgaard   +2 more
openalex   +1 more source

Alterations of circulating innate lymphoid cells in recent‐onset type 1 diabetes

open access: yesClinical &Translational Immunology, Volume 15, Issue 6, 2026.
Circulating innate lymphoid cells (ILC) in patients with recent‐onset type 1 diabetes (T1D) show a chronic activation and a primed phenotype, with overexpression of HLA Class II (ILC1 and ILCP) and dysregulation of costimulatory and migratory mRNA transcripts. Glucose and cytokines (IL‐1β) mediate circulating ILC activation and HLA Class II expression.
Ariadna Roig   +5 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed   +14 more
wiley   +1 more source

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