Results 191 to 200 of about 126,056 (280)

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 20, Page 4876-4893, October 2025.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding   +5 more
wiley   +1 more source

Inhibition of in vitro Cell Migration in Experimental Allergic Encephalomyelitis [PDF]

open access: bronze, 1969
Helene C. Rauch   +3 more
openalex   +1 more source

A safety test for Eastern equine encephalomyelitis vaccine [PDF]

open access: gold, 1967
Sanford Berman   +3 more
openalex   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 19, Page 4466-4489, October 2025.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota   +4 more
wiley   +1 more source

Double Trouble: Aquatic Invasive Plants Can Promote Mosquitoes

open access: yesEcology Letters, Volume 28, Issue 10, October 2025.
ABSTRACT Human activities continue to facilitate biological invasions, profoundly impacting our environment and economy. Plants and insects constitute the majority of invasions to date, with facilitative links established between them, particularly in terrestrial habitats.
Tressia Chikodza   +6 more
wiley   +1 more source

Altered effort and deconditioning are not valid explanations of myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]

open access: yesNat Commun
Davenport TE   +13 more
europepmc   +1 more source

Diagnostic Yield of Anti‐Neuronal Antibody Testing in Patients Suspected of an Infectious Encephalitis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 10, October 2025.
In a retrospective analysis of suspected autoimmune encephalitis (AIE) cases from a prospective cohort including patients with an acute presentation, nine cases of antibody‐positive AIE were identified during hospitalization. Extensive additional anti‐neuronal antibody testing did not yield additional cases of antibody‐positive AIE. ABSTRACT Background
Liora ter Horst   +15 more
wiley   +1 more source

Relationship between post-COVID-19 symptoms and daily physical activity. [PDF]

open access: yesFront Rehabil Sci
Sarmento A   +4 more
europepmc   +1 more source

Co‐Design of a Weekly Meal Box for Neurological Conditions: Findings From Consumer and Healthcare Provider Collaborative Workshops

open access: yesHealth Expectations, Volume 28, Issue 5, October 2025.
ABSTRACT Introduction This study explores the collaborative co‐design process for developing a weekly meal box tailored for individuals with neurological conditions. Recognising the critical role of nutrition for this community, the research addresses the challenges posed by cognitive and physical impairments in meal preparation. Methods Through two co‐
Joanna Rees   +6 more
wiley   +1 more source

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