Results 31 to 40 of about 302,501 (209)

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

open access: yesEmerging Infectious Diseases, 2012
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue.
Nadine Mestre-Francés   +7 more
doaj   +1 more source

Pruritus is a common feature in sheep infected with the BSE agent. [PDF]

open access: yes, 2008
BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Vidal-Diez, Alberto   +50 more
core   +1 more source

Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction

open access: yesPathogens, 2013
Kuru, the first human transmissible spongiform encephalopathy was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). In this review, I briefly summarize the history of this seminal discovery along its epidemiology, clinical picture ...
Pawel P. Liberski
doaj   +1 more source

BSE case associated with prion protein gene mutation. [PDF]

open access: yesPLoS Pathogens, 2008
Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy (TSE) of cattle and was first detected in 1986 in the United Kingdom. It is the most likely cause of variant Creutzfeldt-Jakob disease (CJD) in humans.
Jürgen A Richt, S Mark Hall
doaj   +1 more source

Genetics of Prion Disease in Cattle

open access: yesBioinformatics and Biology Insights, 2015
Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk.
Brenda M. Murdoch, Gordon K. Murdoch
doaj   +1 more source

Hypotheses on the origin and transmission of BSE

open access: yesVeterinární Medicína, 2001
EC Health & Consumer Protection Directorate-General recently published an important document based on papers and reviews discussed by members of TSE/BSE ad hoc group.
K. Hruška
doaj   +1 more source

Isolation of Prion with BSE Properties from Farmed Goat

open access: yesEmerging Infectious Diseases, 2011
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that include variant Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE) in cattle.
John Spiropoulos   +7 more
doaj   +1 more source

A quantitative assessment of the prion risk associated with wastewater from carcase-handling facilities [PDF]

open access: yes, 2013
Wastewater from facilities processing livestock that may harbor transmissible spongiform encephalopathies (TSEs) infectivity is permitted under license for application to land where susceptible livestock may have access. Several previous risk assessments
Adkin, A.   +2 more
core   +4 more sources

Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes. [PDF]

open access: yesPLoS Pathogens, 2008
The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in ...
Guerino Lombardi   +17 more
doaj   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

open access: yes, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J.   +8 more
core   +1 more source

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