Results 21 to 30 of about 10,114 (213)

Conversion of the BASE prion strain into the BSE strain: the origin of BSE?

PLoS Pathogens, 2007
Atypical neuropathological and molecular phenotypes of bovine spongiform encephalopathy (BSE) have recently been identified in different countries.
Raffaella Capobianco, Cristina Casalone, Silvia Suardi, Michela Mangieri, Claudia Miccolo, Lucia Limido, Marcella Catania, Giacomina Rossi, Giuseppe Di Fede, Giorgio Giaccone, Maria Grazia Bruzzone, Ludovico Minati, Cristiano Corona, Pierluigi Acutis, Daniela Gelmetti, Guerino Lombardi, Martin H Groschup, Anne Buschmann, Gianluigi Zanusso, Salvatore Monaco, Maria Caramelli, Fabrizio Tagliavini   +21 more
doaj   +1 more source

Candidate Cell Substrates, Vaccine Production, and Transmissible Spongiform Encephalopathies

Emerging Infectious Diseases, 2011
Transmissible spongiform encephalopathy (TSE) agents have contaminated human tissue–derived medical products, human blood components, and animal vaccines.
Pedro Piccardo, Larisa Cervenakova, Irina Vasilyeva, Oksana Yakovleva, Igor Bacik, Juraj Cervenak, Carroll McKenzie, Lubica Kurillova, Luisa Gregori, Kitty Pomeroy, David M. Asher   +10 more
doaj   +1 more source

State-of-the-art review of goat TSE in the European Union, with special emphasis on PRNP genetics and epidemiology [PDF]

, 2009
Scrapie is a fatal, neurodegenerative disease of sheep and goats. It is also the earliest known member in the family of diseases classified as transmissible spongiform encephalopathies (TSE) or prion diseases, which includes Creutzfeldt-Jakob disease in ...
Olivier Andreéoletti, Groschup, Martin H., Simone Peletto, Foster, James, Barillet, F., Acin, Cristina, Pierluigi Acutis, Peletto, S., Langeveld, J., Theodoros Sklaviadis, Keulen, L.J.M., van, Bossers, Alex, Vaccari, G., Van Keulen, Lucien, Foster, J., Acin, C., Cristina Acin, Andreoletti, O., Jan Langeveld, Goldmann, Wilfred, Umberto Agrimi, Sklaviadis, T., Vaccari, Gabriele, Langeveld, Jan, van Keulen, L., Groschup, M.H., Peletto, Simone, Bossers, A., Gabriele Vaccari, James Foster, Panagiotidis, C.H., Cynthia H. Panagiotidis, Alex Bossers, Badiola, J. J., Badiola, J.J., van Keulen, L.J.M., Juan J. Badiola, Francis Barillet, Sklaviadis, Theodoros, Barillet, Francis, Langeveld, J.P.M., Wilfred Goldmann, Panagiotidis, Cynthia H., Acutis, Pierluigi, Andreeoletti, O., Badiola, Juan J., Goldmann, W., Panagiotidis, C. H., Groschup, M. H., Andreoletti, Olivier, Acutis, P., Agrimi, Umberto, Lucien Van Keulen, Martin H. Groschup, Agrimi, U.   +54 more
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Diagnosis of bovine spongiform encephalopathy: A review [PDF]

Veterinary Quarterly, 2000
Cows affected with bovine spongiform encephalopathy (BSE) display chronic neurological signs consisting of behavioural changes, abnormalities of posture and movement, and/or hyperaesthesia. At present, there are no laboratory test available to diagnose BSE in the live animal. In this article, we describe the post-mortem diagnostic examination of brains
van Keulen, L.J.M., Langeveld, J.P.M., Garssen, G.J., Jacobs, J.G., Schreuder, B.E.C., Smits, M.A.   +5 more
openaire   +3 more sources

Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model

Emerging Infectious Diseases, 2012
We report transmission of atypical L-type bovine spongiform encephalopathy to mouse lemurs after oral or intracerebral inoculation with infected bovine brain tissue.
Nadine Mestre-Francés, Simon Nicot, Sylvie Rouland, Anne-Gaëlle Biacabe, Isabelle Quadrio, Armand Perret-Liaudet, Thierry Baron, Jean-Michel Verdier   +7 more
doaj   +1 more source

BSE case associated with prion protein gene mutation. [PDF]

PLoS Pathogens, 2008
Bovine spongiform encephalopathy (BSE) is a transmissible spongiform encephalopathy (TSE) of cattle and was first detected in 1986 in the United Kingdom. It is the most likely cause of variant Creutzfeldt-Jakob disease (CJD) in humans.
Jürgen A Richt, S Mark Hall
doaj   +1 more source

Pruritus is a common feature in sheep infected with the BSE agent. [PDF]

, 2008
BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Vidal-Diez, Alberto, Chaplin, Melanie J., Simmons, MM, Marion M Simmons, Chaplin, Melani J., Dexter, Glenda, Vidal-Diez, A, Martin Jeffrey, Christine Berthelin-Baker, Bone Gemma, Melanie J Chaplin, Glenda Dexter, Konold Timm, Tortosa Méndez, Raül, Peter Hill, Simmons Marion M, Simmons, Marion M., Tortosa Raul, Chaplin Melanie J, Davis Andrew, Berthelin-Baker, C, Bellworthy, SJ, Dexter Glenda, Bellworthy Susan J, Chaplin, MJ, Susan J Bellworthy, Bellworthy, Susan J., Timm Konold, Hill, P, Berthelin-Baker Christine, Gemma Bone, Raul Tortosa, Tortosa, R, Vidal-Diez Alberto, Jeffrey Martin, Hill, Peter, Konold, T, Hill Peter, Tortosa, Raul, Berthelin-Baker, Christine, Dexter, G, Davis, Andrew, Bone, G, Davis, A, Vidal Díez, Alberto, Jeffrey, M, Bone, Gemma, Jeffrey, Martin, Konold, Timm, Andrew Davis, Alberto Vidal-Diez   +50 more
core   +1 more source

Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction

Pathogens, 2013
Kuru, the first human transmissible spongiform encephalopathy was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). In this review, I briefly summarize the history of this seminal discovery along its epidemiology, clinical picture ...
Pawel P. Liberski
doaj   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie

, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A., A. Bossers, Y. Tang, Sauer, M., M. Sauer, L. J. M. van Keulen, J. P. M. Langeveld, J. G. Jacobs, Keulen, L.J.M., van, van Keulen, L.J.M., Tang, Y., Jacobs, J.G., Langeveld, J.P.M.   +12 more
core   +1 more source

Genetics of Prion Disease in Cattle

Bioinformatics and Biology Insights, 2015
Bovine spongiform encephalopathy (BSE) is a prion disease that is invariably fatal in cattle and has been implicated as a significant human health risk.
Brenda M. Murdoch, Gordon K. Murdoch
doaj   +1 more source