Results 51 to 60 of about 19,991 (204)
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform ...
Kurt C VerCauteren +4 more
doaj +1 more source
Abstract Trust in regulatory regimes is essential for democratic legitimacy and regulatee compliance. This is particularly relevant in multilevel systems such as the European Union. This study examines the interplay of individual‐ and country‐level factors that contribute to stakeholder trust in the European Food Safety Authority (EFSA).
Jana Gómez Díaz
wiley +1 more source
Methods for differentiating prion types in food-producing animals [PDF]
Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrPSc).
Gough, Kevin C. +3 more
core +2 more sources
ABSTRACT This article analyses the recent expansion of Argentina's beef exports in the context of China's emergence as the world's leading beef importer and the principal destination for Argentine exports. It examines shifts in production, export orientation and domestic consumption, and analyses the export‐oriented fractions of meat capital that have ...
Emilia Ormaechea +2 more
wiley +1 more source
Use of bovine recombinant prion protein and real-time quaking-induced conversion to detect cattle transmissible mink encephalopathy prions and discriminate classical and atypical L- and H-Type bovine spongiform encephalopathy. [PDF]
Prions are amyloid-forming proteins that cause transmissible spongiform encephalopathies through a process involving conversion from the normal cellular prion protein to the pathogenic misfolded conformation (PrPSc).
Soyoun Hwang +2 more
doaj +1 more source
ABSTRACT Using data from a long‐term survey of senior civil servants (1970–2021), this study investigates the declining share of jurists in federal ministerial departments in Germany. The mechanisms driving this trend and its subsequent effects are discussed from an organizational perspective, highlighting the influence of environmental pressure and ...
Marian Döhler
wiley +1 more source
Atypical Bovine Spongiform Encephalopathies, France, 2001–2007
In France, through exhaustive active surveillance, ≈17.1 million adult cattle were tested for bovine spongiform encephalopathy from July 2001 through July 2007; ≈3.6 million were >8 years of age.
Anne-Gaëlle Biacabe +4 more
doaj +1 more source
Biodegradation of bovine spongiform encephalopathy prions in compost
To reduce the transmission risk of bovine spongiform encephalopathy prions (PrPBSE), specified risk materials (SRM) that can harbour PrPBSE are prevented from entering the feed and food chains.
Shanwei Xu +7 more
doaj +1 more source
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source

