Results 11 to 20 of about 235,104 (268)

Monoclonal Antibody Therapy in Neuromyelitis Optica Spectrum Disorders: a Meta-analysis of Randomized Control Trials

Frontiers in Pharmacology, 2021
Background: To update the efficacy and safety data of monoclonal antibodies for the treatment of neuromyelitis optica spectrum disorders (NMOSD) and explore the differences in the effect of treatment between patients seropositive and seronegative for ...
Fanxin Kong, Fanxin Kong, Jianjun Wang, Jianjun Wang, Haotao Zheng, Haotao Zheng, Haobin Cai, Haobin Cai, Jun Hua, Jun Hua, Liling Li, Liling Li   +11 more
doaj   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A., A. Bossers, Y. Tang, Sauer, M., M. Sauer, L. J. M. van Keulen, J. P. M. Langeveld, J. G. Jacobs, Keulen, L.J.M., van, Tang, Y., Jacobs, J.G., Langeveld, J.P.M.   +11 more
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Homocysteine in cerebrovascular disease: An independent risk factor for subcortical vascular encephalopathy [PDF]

, 2001
Hyperhomocysteinemia is a risk factor for obstructive large-vessel disease. Here, we studied plasma concentrations of homocysteine and vitamins in patients suffering from subcortical vascular encephalopathy (SVE), a cerebral small-vessel disease leading ...
Ragoschke, Andreas, Bertsch, Thomas, Casarin, Wendy, Walter, Silke, Aufenanger, Johannes, Mielke, Orell, Höly, Sabine, Kuehl, Sandra, Muehlhauser, Frank, Fassbender, Klaus, Zimmer, Wilma   +10 more
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Bilateral corpus callosum and corona radiata infarction due to cerebral venous sinus thrombosis presenting as headache and acute reversible aphasia: a rare case report

BMC Neurology, 2020
Background Cerebral venous sinus thrombosis (CVST), a rare cause of cerebral infarction, is often unrecognized at initial presentation. We report the case of a patient with bilateral corpus callosum and corona radiata infarction due to cerebral venous ...
Rui Lan, Yun-zhi Ma, Xiao-ming Shen, Ji-tao Wu, Chun-qing Gu, Yong Zhang   +5 more
doaj   +1 more source

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken [PDF]

, 2011
Background: Transmission of the prion disease bovine spongiform encephalopathy (BSE) occurred accidentally to cattle and several other mammalian species via feed supplemented with meat and bone meal contaminated with infected bovine tissue.
Stack Michael J, Robert B Green, Paul R Webb, Simmons, M.M., Timm Konold, Spencer, Y.I., Moore Jo, Marion M Simmons, Ian Dexter, Moore, J., Michael Dawson, Jo Moore, Chaplin, M.J., Webb, P.R., Dexter, I., Wells Gerald AH, Austin, A.R., Dawson, M., Austin Anthony R, Gerald AH Wells, Michael J Stack, Anthony R Austin, Wells, G.A.H, Green Robert B, Langeveld, J.P.M., Ian W Blamire, Stack, M.J., Melanie J Chaplin, Simmons, M., Konold Timm, Dawson Michael, Spencer Yvonne I, Hawkins, S.A.C., Konold, T., Simmons Marion M, Chaplin Melanie J, Hawkins Stephen AC, Dexter Ian, Blamire Ian W, Langeveld Jan PM, Jan PM Langeveld, Webb, P.R.I., Yvonne I Spencer, Green, R.B., Blamire, I.W., Webb Paul R, Stephen AC Hawkins   +46 more
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Recent advances in targeting calcitonin gene-related peptide for the treatment of menstrual migraine

Medicine, 2022
. Menstrual migraine (MM) has a longer duration and higher drug resistance than non-perimenstrual migraine. Calcitonin gene-related peptide (CGRP) and CGRP receptors are expressed in the peripheral and central nervous systems throughout the ...
Yan Jiang, MMed, Zhen-Lun Huang, BMed
doaj   +1 more source

Pilot randomized trial of therapeutic hypothermia with serial cranial ultrasound and 18-22 month follow-up for neonatal encephalopathy in a low resource hospital setting in Uganda: study protocol [PDF]

, 2011
Background: There is now convincing evidence that in industrialized countries therapeutic hypothermia for perinatal asphyxial encephalopathy increases survival with normal neurological function. However, the greatest burden of perinatal asphyxia falls in
Allen, Elizabeth, Allen Elizabeth, Cornelia F Hagmann, Jacobs Ian, Hagmann, Cornelia F., Nakakeeto Margaret, Elbourne, Diana, Jacobs, Ian, Ian Jacobs, Costello, Anthony, Frances Cowan, Acolet Dominique, Nicola J Robertson, Acolet, Dominique, Anthony Costello, Cowan Frances, Cowan, Frances, Acolet, D, Elbourne, D, Nyombi, Natasha, Robertson, Nicola J., Hagmann Cornelia F, Dominique Acolet, Robertson Nicola J, Robertson, NJ, Diana Elbourne, Margaret Nakakeeto, Nyombi Natasha, Cowan, F, Jacobs, I, Costello, A, Nakakeeto, Margaret, Robertson, Nicola J, Elbourne Diana, Hagmann, Cornelia F, Nakakeeto, M, Elizabeth Allen, Hagmann, CF, Nyombi, N, Allen, E, Costello Anthony, Natasha Nyombi   +41 more
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Eosinophil-to-monocyte ratio is a potential biomarker in the prediction of functional outcome among patients with acute ischemic stroke

BMC Neuroscience, 2021
Background It has been shown that eosinophils are decreased and monocytes are elevated in patients with acute ischemic stroke (AIS), but the impact of eosinophil-to-monocyte ratio (EMR) on clinical outcomes among AIS patients remains unclear. We aimed to
Shuhong Yu, Yi Luo, Tan Zhang, Chenrong Huang, Yu Fu, Qiang Zhang, Fangyue Zeng, Hao Huang, Chunyuan Zhang, Zhiliang Guo   +9 more
doaj   +1 more source

Clinical safety and possible efficacy of tirofiban in combination with intravenous thrombolysis by recombinant tissue plasminogen activator for early treatment of capsular warning syndrome (CWS)

Frontiers in Neuroscience, 2022
The purpose of this study was to assess the efficacy and safety of the combination of tirofiban with intravenous thrombolysis (IVT) in treating patients with capsular warning syndrome (CWS) who failed to respond to the treatment of intravenous ...
Yunzhu Liu, Shiyong Li, Dongdong Hao, Zhongping Zhang, Yongxin Yi, Jiayang Fang, Weizhi Lin, Min Zhang   +7 more
doaj   +1 more source

Multiple intracranial enlarging dissecting aneurysms: a case report

BMC Neurology, 2023
Background Cases of multiple cerebral aneurysms are rare. In this case report, we describe a male patient with multiple, enlarging, and ruptured aneurysms. The two aneurysms were believed to be dissecting aneurysms.
Yingbin Li, Xiaoxin Bai, Huai Tu, Zhimin Zou, Yan Huang, Jun Cai   +5 more
doaj   +1 more source