Results 41 to 50 of about 309,185 (347)

Copper deposition in Wilson’s disease causes male fertility decline by impairing reproductive hormone release through inducing apoptosis and inhibiting ERK signal in hypothalamic-pituitary of mice

Frontiers in Endocrinology, 2022
Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism characterized by liver and central nervous system dysfunction. Considerable evidence suggests that infertility is also very common in male patients with WD, but the exact ...
Tingting Wang, Limin Wu, Qiuying Chen, Kuiyu Chen, Fang Tan, Jiabo Liu, Xiang Liu, Hui Han   +7 more
doaj   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Hepatic encephalopathy

Saudi Journal of Gastroenterology, 2012
Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension. One of these recurrent and difficult to treat complications is hepatic encephalopathy.
Wissam Bleibel, Abdullah M. S. Al-Osaimi
openaire   +3 more sources

Hemorrhagic Posterior Reversible Encephalopathy Syndrome as a Manifestation of COVID-19 Infection

American Journal of Neuroradiology, 2020
SUMMARY: We describe 2 hospitalized patients with confirmed coronavirus 19 (COVID-19) infection in whom brain imaging showed hemorrhagic posterior reversible encephalopathy syndrome, and we discuss the possible reasons for these findings and their ...
A. Franceschi, Osama Ahmed, L. Giliberto, M. Castillo   +3 more
semanticscholar   +1 more source

Encephalopathy with Hypothyroidism [PDF]

Journal of the Royal Society of Medicine, 2004
An occasional associated feature in Hashimoto's thyroiditis is encephalopathy. Whether this amounts to ‘Hashimoto's encephalopathy’ is disputed.
Claire Warren, I M S Sawhney
openaire   +2 more sources

Sepsis-Associated Encephalopathy: From Delirium to Dementia?

Journal of Clinical Medicine, 2020
Sepsis is a major cause of death in intensive care units worldwide. The acute phase of sepsis is often accompanied by sepsis-associated encephalopathy, which is highly associated with increased mortality.
Ha-Yeun Chung, Jonathan Wickel, F. Brunkhorst, C. Geis   +3 more
semanticscholar   +1 more source

Yi-nao-jie-yu Prescription Exerts a Positive Effect on Neurogenesis by Regulating Notch Signals in the Hippocampus of Post-stroke Depression Rats

Frontiers in Psychiatry, 2018
Post-stroke depression (PSD) is one of the most frequent complications of stroke. The Yi-nao-jie-yu prescription (YNJYP) is an herbal prescription widely used as a therapeutic agent against PSD in traditional Chinese medicine.
Huiling Tian, Xiaoli Li, Qisheng Tang, Wen Zhang, Qingmeng Li, Xinyue Sun, Ruizhen Zhao, Chongyang Ma, Haipeng Liu, Yushan Gao, Fei Han   +10 more
doaj   +1 more source

Comprehensive analysis of the coding and non-coding RNA transcriptome expression profiles of hippocampus tissue in tx-J animal model of Wilson's disease

Scientific Reports, 2023
Wilson's disease (WD) is an autosomal recessive disorder with a genetic basis. The predominant non-motor symptom of WD is cognitive dysfunction, although the specific genetic regulatory mechanism remains unclear.
Dan Wang, Daojun Xie, Juan Zhang, Biao Cai, Bo Yang, Lei Zhou, Xiaofeng Huang   +6 more
doaj   +1 more source

Retraction Note: Tripartite motif-containing 14 (TRIM14) promotes epithelial-mesenchymal transition via ZEB2 in glioblastoma cells

Journal of Experimental & Clinical Cancer Research, 2023
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-019-1070-x.
Shuang Feng, Xiaomin Cai, Yangyang Li, Xiaoguang Jian, Linxin Zhang, Bin Li   +5 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source