Results 81 to 90 of about 216,601 (314)
British Journal of Clinical Pharmacology, EarlyView.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Frontiers in MedicineHepatolenticular Degeneration (HLD) is a rare condition caused by a genetic copper metabolism disorder and a basal ganglia-dominated degenerative brain disease. Its characteristic clinical features include progressive extrapyramidal symptoms, psychiatric
Zhuang Tao +5 more
doaj +1 more source
Revista Clínica Española (English Edition), 2020 Rosales-Castillo, Antonio +1 more
openaire +3 more sources
Efficacy, safety and cost‐effectiveness of CAR‐T therapy
British Journal of Clinical Pharmacology, EarlyView.CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher +7 more
wiley +1 more source
Recent Insights Into Alzheimer's Disease: Advances in Pathophysiology and Therapeutic Strategies
Brain Health, EarlyView.ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative disorder driven by interplay among amyloid‐β (Aβ) plaques, tau neurofibrillary tangles, inflammation and comorbid pathologies. Recent advances in biomarkers and therapeutic approvals have reshaped our understanding of its pathophysiology and treatment landscape.
Jiong Shi +3 more
wiley +1 more source
Brain Health, EarlyView.ABSTRACT The World Health Organization (WHO) defines brain health as the maintenance of optimal brain integrity, good mental state, and cognitive function without significant neuropsychiatric disease. Early childhood is a critical period for brain development, which were influenced by early experiences, nutrition, and environmental factors. Disruptions
Yu Ma +5 more
wiley +1 more source
Clinical analysis of Wallenberg's syndrome
Chinese Journal of Contemporary Neurology and Neurosurgery, 2019 Objective To summarize the clinical features of Wallenberg syndrome (WS). Methods Clinical manifestations, imaging features, etiology and predisposing factors, treatment and prognosis of 36 WS patients from March 2015 to October 2017 were retrospectively
Jie HU +4 more
doaj
Chronic Diseases and Translational Medicine, EarlyView.Nonlinear associations of serum sodium levels with cardiovascular (A) and all‐cause mortality (B)among 32,837 adults. Nonlinear associations of serum potassium levels with cardiovascular (C) and all‐cause mortality (D) among 32,837 adults. ABSTRACT Background This study aimed to investigate the associations of serum sodium and potassium levels within ...
Haofeng Zhang +7 more
wiley +1 more source
Unexpected clinical outcomes following the implementation of a standardised order set for hepatic encephalopathy [PDF]
, 2021 Mandip Kc +3 more
openalex +1 more source
Catalytic Amyloids: Turning Fibrils Into Biocatalysts
Chemistry – A European Journal, EarlyView.Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito +3 more
wiley +1 more source