Results 81 to 90 of about 381,364 (391)

Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]

open access: yes, 2005
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson   +46 more
core   +2 more sources

Astragaloside IV Treats Parkinson’s Disease by Regulating the Proliferation and Differentiation of NSCs through the SHH–Nurr1 Pathway

open access: yesStem Cells International
Recently, there has been a surge of interest in enhancing the differentiation of neural stem cells (NSCs) and supplementing dopamine neurons as a potential treatment for Parkinson’s disease, the second most prevalent neurodegenerative disorder.
Zicong Wu   +3 more
doaj   +1 more source

Prevalence of diabetes in the USA from the perspective of demographic characteristics, physical indicators and living habits based on NHANES 2009-2018

open access: yesFrontiers in Endocrinology, 2023
ObjectiveTo determine differences in DM in the U.S. population according to demographic characteristics, physical indicators and living habits.Methods23 546 participants in the 2009 to 2018 National Health and Nutrition Examination Survey (NHANES) who ...
Ling Fang   +3 more
doaj   +1 more source

Comparison of transjugular intrahepatic portosystemic shunt with covered stent and balloon-occluded retrograde transvenous obliteration in managing isolated gastric varices [PDF]

open access: yes, 2017
OBJECTIVE: Although a transjugular intrahepatic portosystemic shunt (TIPS) is commonly placed to manage isolated gastric varices, balloon-occluded retrograde transvenous obliteration (BRTO) has also been used. We compare the long-term outcomes from these
Kim, Seung Kwon   +3 more
core   +3 more sources

Hepatic encephalopathy—Definition, nomenclature, diagnosis, and quantification: Final report of the Working Party at the 11th World Congresses of Gastroenterology, Vienna, 1998

open access: yesHepatology, 2002
Research on hepatic encephalopathy is hampered by the imprecise definition of this disabling complication of liver disease. Under this light, the Organisation Mondiale de Gastroentérologie commissioned a Working Party to reach a consensus in this area ...
P. Ferenci   +5 more
semanticscholar   +1 more source

Treatment‐related adverse events of antibody–drug conjugates in clinical trials: A systematic review and meta‐analysis

open access: yesCancer, Volume 129, Issue 2, Page 283-295, 15 January 2023., 2023
Abstract Background Antibody–drug conjugates (ADCs) have complex molecular structures and have been tested in numerous clinical trials. Therefore, understanding the mechanisms of their toxicity when applied in medical practice is of high importance. Methods In a systematic review and meta‐analysis of data gathered from different scientific databases ...
Youwen Zhu   +3 more
wiley   +1 more source

The risk of bleeding and encephalopathy in surgical patients with liver cirrhosis [PDF]

open access: yes, 2019
Liver cirrhosis is a disease with an increasing incidence. Surgical procedures in patients with cirrhosis are also increasing, due to a longer life expectancy in these patients and also to the improvement of therapeutic and diagnostic resources ...
Bacalbașa, Nicolae   +9 more
core   +1 more source

Ammonia toxicity: from head to toe? [PDF]

open access: yes, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan   +6 more
core   +1 more source

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome

open access: yesAnnals of Neurology, 2020
SCN8A encephalopathy is a developmental and epileptic encephalopathy (DEE) caused by de novo gain‐of‐function mutations of sodium channel Nav1.6 that result in neuronal hyperactivity.
Guy M. Lenk   +13 more
semanticscholar   +1 more source

Current evidence, clinical applications, and future directions of transcranial magnetic stimulation as a treatment for ischemic stroke

open access: yesFrontiers in Neuroscience, 2023
Transcranial magnetic stimulation (TMS) is a non-invasive brain neurostimulation technique that can be used as one of the adjunctive treatment techniques for neurological recovery after stroke.
Li Zhou   +12 more
doaj   +1 more source

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