Results 151 to 160 of about 1,225,935 (368)
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li+11 more
wiley +1 more source
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing+18 more
wiley +1 more source
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang+5 more
wiley +1 more source
History and development prospects of the regional encyclopedia publishing in Russia
Anastasiya Korochkina
doaj +1 more source
Enrichment of extracellular vesicles using Mag-Net for the analysis of the plasma proteome. [PDF]
Wu CC+18 more
europepmc +1 more source
openaire +2 more sources