Results 151 to 160 of about 1,255,561 (338)
Let Them Talk as “Encyclopedia of Russian Life”: Latent «Accursed Questions» on Russian Television (2017) [PDF]
, 2018 Irina I. Volkova +3 more
openalex +1 more source
Advanced Science, EarlyView.This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang +6 more
wiley +1 more source
Causal cues and mediating pathways of potential genetic mechanisms of subarachnoid hemorrhage and intracerebral hemorrhage. [PDF]
Medicine (Baltimore)Wang Y +8 more
europepmc +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Therapeutic targets of L-carnitine against polycystic ovary syndrome and the underlying signaling mechanisms. [PDF]
Medicine (Baltimore)Zhang Y +5 more
europepmc +1 more source
Encyclopedia of Chemistry Laboratory Equipment to Support Basic Chemistry Practicum Learning
, 2022 I Ketut Sudiana
openalex +2 more sources
Advanced Science, EarlyView.Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu +13 more
wiley +1 more source