Results 191 to 200 of about 1,225,935 (368)
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
wiley +1 more source
From gene expression to causal associations: investigating the role of ferroptosis in cataract development. [PDF]
Li C, Yuan XB, Lu YC, Song ZY.
europepmc +1 more source
International Encyclopedia of Pharmacology and Therapeutics [PDF]
Rudolph H. de Jong
openalex +1 more source
This study develops enucleated MSC‐derived microvesicles (Mito@euMVs) to deliver functional mitochondria for optimizing wound repair. By efficiently encapsulating mitochondria, Mito@euMVs rejuvenate hyperglycemia‐induced senescent fibroblasts and HUVECs. Using PVA microneedle patches, the therapeutic efficacy of Mito@euMVs is validated in diabetic rats
Zixuan Dong+3 more
wiley +1 more source
Network pharmacology of the regulation of Th17/Treg cell immune balance in the pathogenesis of arthritis by the combination of Chuanxiong Rhizoma, Radix Angelicae Biseratae and Achyranthis Bidentatae Radix. [PDF]
Chen Z, Yin C, Zhang B, Li Z.
europepmc +1 more source
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen+5 more
wiley +1 more source
Characterization of the Molecular Mechanisms Underlying Lurasidone-Induced Acute Manic Episodes in Bipolar Depression: A Network Pharmacology and Molecular Docking Approach. [PDF]
Li C+9 more
europepmc +1 more source