Results 51 to 60 of about 1,264,841 (338)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
This short paper is the encyclopedia entry on Supply of Money to appear in the second edition of the International Encyclopedia of the Social Sciences. The encyclopedia is edited by William A.
William Barnett
core +3 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
How Adventure Time Fans Understand the True Producer: A Close Analysis of Two Encyclopedic Fan Texts
Transformative Works and Cultures, 2022 Adventure Time fan encyclopedists cataloged the show's final eighty-three episodes on Wikipedia and the Adventure Time Wiki in different ways: the former favored a division handed down by Cartoon Network, whereas the latter favored a division in line ...
Paul Thomas
doaj +1 more source
Anglim\u27s Encyclopedia of religion and the law in America, 2nd ed. (Book Review)
, 2016 A review of Anglim, C.T. (2009). Encyclopedia of religion and the law in America, 2nd ed. Amenia, NY: Grey House Publishing. 847 pp. $165.00.
Laing, John D.
core +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Integrable Systems and Discrete Geometry
, 2005 This is an expository article for Elsevier's Encyclopedia of Mathematical Physics on the subject in the title.
Akhmetshin +15 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
THE LEADER OF THE SOCIALIST-REVOLUTIONARIES. RETURN FROM OBLIVION
Мир новой экономики, 2018 Thanks to rehabilitation and clarification of reputation of people of science, culture, policy the original image of Russia is restored. Prophetic words of A.
BORIS ALEKSEEVICH Myasoyedov
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