Results 71 to 80 of about 1,239,580 (286)

Boosting scientific literacy and learning motivation in elementary students through a contextual plant encyclopedia

open access: yesBiosfer
The low level of science literacy and student motivation demands innovative, relevant, and engaging learning media. This study aims to measure the effectiveness of a contextual-based plant encyclopedia in improving science literacy and student motivation
Aprilia Cyahyani Rupilu, Ika Maryani
doaj   +1 more source

A conversation analytic perspective on Quranic verses and chapters

open access: yesStudies in English Language and Education, 2018
Applying a conversation-analytic framework to Quranic verses and chapters, the current qualitative study sought to shed new lights on the opening and closing verses in The Holy Quran.
Ali Kazemi   +1 more
doaj   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu   +6 more
wiley   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

A Comparative Study of the Encyclopedia Compilation Process in the Encyclopedia World of Islam & Encyclopedia of Islam – Leiden

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2015
Purpose: the present paper compares two reference books the Encyclopedia World of Islam &  Encyclopedia  of Islam– Leiden  with regard to the whole process of compiling the encyclopedia, and to conduct an evaluative content analysis .
seyyed ahmad hosseinzadeh   +1 more
doaj  

The attraction of the Fabaceae family encyclopedia book: Educational development research

open access: yesPractice of the Science of Teaching Journal
Critical thinking is one of the 4C skills students need to develop to compete in the 21st-century. Learning planning is focused not only on strategies and human resources, but also on learning resources.
Salsabila Salsabila   +2 more
doaj   +1 more source

Thinking about death: fear or courage [PDF]

open access: yesحکمت سینوی
A wise and appropriate confrontation with death has been the question and concern of many philosophical systems of thought, and various opinions have been presented about the desirability and undesirability of thinking about death and different solutions
Tayebeh Karami
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

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