Results 61 to 70 of about 1,225,935 (368)

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Reduction [PDF]

open access: yes, 2013
This is a contribution to the encyclopedia of systems biology on ...
Kaiser, Marie I.
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

The Locus Ceruleus in PTSD [PDF]

open access: yes, 2009
NO ABSTRACT: This is 750 word encyclopedia ...
Bracha, Dr. H. Stefan   +4 more
core  

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

Population Concentration of Jews in the Cities of Iran From the Saljukid era to the attack of Mongols [PDF]

open access: yesتحقیقات تاریخ اجتماعی, 2011
Despite much demographical information on Jews living in Arab territory of the Islamic era, there is not much information available about the population dispersion of Jews in Iran through the Saljoughi period.
Negar Zeylabi
doaj  

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang   +4 more
wiley   +1 more source

Au commencement était la taxe [PDF]

open access: yesStudia Gilsoniana
In the old days, taxing a commodity meant setting its price (i.e., its "rate") through negotiation, to keep it within the reach of as many people as possible. Taxation was an exceptional measure granted by royal authority to the public, who cherished it.
Marion Sigaut
doaj   +1 more source

Atomismus [PDF]

open access: yes, 2005
Encyclopedia article briefly summarizing the history of atomism from antiquity to ...
Johnson, Monte
core  

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

open access: yesAdvanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez   +8 more
wiley   +1 more source

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