Results 81 to 90 of about 41,046 (283)

Self-Supervised Chinese Ontology Learning from Online Encyclopedias

open access: yesThe Scientific World Journal, 2014
Constructing ontology manually is a time-consuming, error-prone, and tedious task. We present SSCO, a self-supervised learning based chinese ontology, which contains about 255 thousand concepts, 5 million entities, and 40 million facts.
Fanghuai Hu, Zhiqing Shao, Tong Ruan
doaj   +1 more source

The Warped Galaxy ESO 510 G13 Lithograph [PDF]

open access: yes, 2003
This lithograph is part of a series designed to bring the latest Hubble Space Telescope images into the classroom. In the educational activity, In Search of ...

core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Comparative Study on the Joint Biographical Entries within the Iranian Encyclopedia for Young People and Similar printed English Language Encyclopedias [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2017
Purpose: The objective of present study is comparative study of children’s encyclopedias Published in Iran, according to the research variables (entries number, structure, writing, reputation, up-to-dateness, and biography types) for determination of ...
Azadmehr Danesh Fatemieh   +1 more
doaj  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Fossils: Digging Into the Past

open access: yes, 2017
Fossils collected in Renaissance collection cabinets were items of wonder and curiosity. Although sometimes mistaken for other pieces of naturalia, they were widely collected by owners of princely cabinets and scholarly collections.Though naturalists and
Caccioppoli, Sidney N.
core  

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Secondary Sources: Top Ten [PDF]

open access: yes, 2005
Secondary sources are a legal researcher\u27s best friend. They are a great place to begin researching a new topic as they provide a framework for understanding the subject.
Zago, Susan Drisko
core   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

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