Results 121 to 130 of about 269,528 (258)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Pneumatic-Cable-Hybrid-Driven Multi-Mechanism End Effector and Cross-Surface Validation. [PDF]

Biomimetics (Basel)
Wang Z, Weng Z, Zhang P, Jiang W, Deng N, Wang Z.   +5 more
europepmc   +1 more source

A Constant-Force End-Effector With Online Force Adjustment for Robotic Ultrasonography. [PDF]

IEEE Robot Autom Lett, 2021
Bao X, Wang S, Housden R, Hajnal J, Rhode K.   +4 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

End-Effector Robot-Assisted Gait Training in Quadruple Amputees: Two Case Reports. [PDF]

Ann Rehabil Med
Kim Y, Oh Y, Shin S, Oh D, Cho SI, Jeong J, Yoo J.   +6 more
europepmc   +1 more source

Comparing the Lower-Limb Muscle Activation Patterns of Simulated Walking Using an End-Effector-Type Robot with Real Level and Stair Walking in Children with Spastic Bilateral Cerebral Palsy. [PDF]

Sensors (Basel), 2023
Ahn Y, Hong J, Shim D, Choi JO, Rha DW.
europepmc   +1 more source

A laser tracking dynamic robot metrology instrument [PDF]

Research work over several years has resulted in the development of a laser tracking instrument capable of dynamic 3-D measurements of robot end-effector trajectories.
Mayer, J. R. R., Parker, G. A.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Effects of Clinical Applications of Robot-Assisted Therapy Methods: End-Effector, Fixed Exoskeleton, and Wearable Exoskeleton on Functional Activities in Stroke Patients. [PDF]

Life (Basel)
Lee JH.
europepmc   +1 more source

Collision Localization and Classification on the End-Effector of a Cable-Driven Manipulator Applied to EV Auto-Charging Based on DCNN-SVM. [PDF]

Sensors (Basel), 2022
Lin H, Quan P, Liang Z, Lou Y, Wei D, Di S.   +5 more
europepmc   +1 more source