HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Design and control of a low-cost non-backdrivable end-effector upper limb rehabilitation device. [PDF]
Li F +7 more
europepmc +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Coupling of Limit Switch Sensors and Stepper Motors with Acoustic Feedback for Positioning of a Cartesian Robot End Effector in the Study of Musical Instruments. [PDF]
Tokarczyk D +3 more
europepmc +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
A compensation strategy of end-effector pose precision based on the virtual constraints for serial robots with RDOFs. [PDF]
Ba K +6 more
europepmc +1 more source
Design and Integration of a Parallel, Soft Robotic End-Effector for Extracorporeal Ultrasound. [PDF]
Lindenroth L +5 more
europepmc +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Airborne Acoustic Vortex End Effector-based Contactless, Multi-mode, Programmable Control of Object Surfing. [PDF]
Li T +11 more
europepmc +1 more source
Design of an end-effector for robot-assisted ultrasound-guided breast biopsies. [PDF]
Welleweerd MK +4 more
europepmc +1 more source

