Results 191 to 200 of about 2,836,766 (304)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Motion/force transmission performance analysis and optimal design of closed-chain end-effector for steel arch splicing robot. [PDF]

Sci Rep
Chen H, He Y, Yu X, Xu Z, Zheng X.
europepmc   +1 more source

Model Calibration for a Rigid Hexapod-Based End-Effector with Integrated Force Sensors. [PDF]

Sensors (Basel), 2021
Friedrich C, Ihlenfeldt S.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Effect of end-effector robot training on lower limb motor function and balance in stroke patients: a systematic review and meta-analysis. [PDF]

Front Neurol
Lou Z, Wang F, Guan D, Hu Z, Wei C, Zhang X.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

New Rehabilitation Assessment Method of the End-Effector Finger Rehabilitation Robot Based on Multi-Sensor Source. [PDF]

Healthcare (Basel), 2021
Wang H, Chen P, Li Y, Sun B, Liao Z, Niu B, Niu J.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Early end-effector-based gait training in non-ambulatory patients with visuospatial neglect after subacute stroke. [PDF]

Front Neurol
Gorsler A, Ernst D, Grittner U, Harnack D, Koßmehl P, Mehrholz J, Mueske C, Schneider P, Kuelzow N.   +8 more
europepmc   +1 more source

A self-aligning end-effector robot for individual joint training of the human arm. [PDF]

J Rehabil Assist Technol Eng, 2021
Balasubramanian S, Guguloth S, Mohammed JS, Sujatha S.   +3 more
europepmc   +1 more source