Results 61 to 70 of about 269,528 (258)
, 1978 A wrist joint assembly is provided for use with a mechanical manipulator arm for finely positioning an end-effector carried by the wrist joint on the terminal end of the manipulator arm. The wrist joint assembly is pivotable about a first axis to produce
Johnson, J. D., Kersten, L.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Development of kinematic equations and determination of workspace of a 6 DOF end-effector with closed-kinematic chain mechanism [PDF]
This report presents results from the research grant entitled Active Control of Robot Manipulators, funded by the Goddard Space Flight Center, under Grant NAG5-780, for the period July 1, 1988 to January 1, 1989. An analysis is presented of a 6 degree-of-
Nguyen, Charles C., Pooran, Farhad J.
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Microcomputer Aided Selection Of Robot Manipulators [PDF]
, 1991 This paper presents two programs for microcomputer aided assessment of the performance of robot manipulators. The first program automatically generates robot models based on user-supplied kinematic parameters.
Abdel Rahman, T. M
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Learning-based position control of a closed-kinematic chain robot end-effector [PDF]
A trajectory control scheme whose design is based on learning theory, for a six-degree-of-freedom (DOF) robot end-effector built to study robotic assembly of NASA hardwares in space is presented.
Nguyen, Charles C., Zhou, Zhen-Lei
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Method and apparatus for releasably connecting first and second objects [PDF]
, 1991 The apparatus and method are disclosed for releasably connecting first and second objects, where a magnetic end effector may include at least one elongated pin number, a proximal end of which is connected to the first object and the distal end of which ...
Monford, Leo G., Jr.
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Self-Organizing Neural Model of Motor Equivalent Reaching and Tool Use by a Multijoint Arm [PDF]
, 1992 This paper describes a self-organizing neural model for eye-hand coordination. Called the DIRECT model, it embodies a solution of the classical motor equivalence problem. Motor equivalence computations allow humans and other animals to flexibly employ an
Bullock, Daniel +2 more
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