Results 111 to 120 of about 2,383,058 (360)
The end-of-life of bridges: Integrating functional, technical and economic perspective
, 2023 Anna‐Maria Hartmann, Jan Bakker
openalex +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Experiences of Gay, Lesbian, Bisexual and Transgender People around End-of-Life Care [PDF]
, 2010 All States and Territories in Australia have implemented legislation relating to end-of-life decision-making and substitute judgment. However, reports to relevant legal and community services indicate that many gay, lesbian, bisexual and transgender ...
Colleen Cartwright +2 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Supporting Homeless People with Advanced Liver Disease Approaching the End of Life [PDF]
, 2011 Of the thousands of people that St Mungo's supports each year, around 50 will die in their care, with advanced liver failure being the most common cause.
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BMC Palliative CareBackground People experiencing homelessness access specialist palliative care late in their illness trajectory, if at all. There is also little evidence they receive generalist palliative care or are given opportunities to engage in Advance Care Planning.
Merryn Gott +6 more
doaj +1 more source
End-of-Life Care Decisions: Importance of Reviewing Systems and Limitations After 2 Recent North American Cases [PDF]
, 2012 Christopher M. Burkle, Jeffre J. Benson
openalex +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Discharge from critical care into the community for end-of-life care [PDF]
, 2017 This article discusses the considerations and actions taken to facilitate the discharge of a ventilated end-of-life patient called Michael, whose name has been changed for confidentiality, from a critical care unit (CCU) to his expressed preferred place ...
Chambers, Anthony
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source