Results 131 to 140 of about 167,114,309 (280)

Reforms recommended for end of life choices

, 2016
The Victorian Parliament\u27s Legal and Social Issues Committee to inquire into, consider and report, no later than 31 May 2016, on the need for laws in Victoria to allow citizens to make informed decisions regarding their own end of life choices and, in
Parliament of Victoria- Legal and Social Issues Committee
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PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A mindful approach with end-of-life thoughts

Frontiers in Psychology, 2014
Francesco ePagnini, Francesco ePagnini, Francesco ePagnini, Deborah ePhillips, Ellen eLanger   +4 more
doaj   +1 more source

The Role of Social Workers in the End-of-Life Debate

Columbia Social Work Review, 2019
Although many articles and books discuss the ethics of end-of-life issues, few publications are written specifi cally for social workers and social work students.
Jennifer Zaleski
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

End-of-life disposal in inclined geosynchronous orbits

, 2020
The first version (2002) of the Mitigation Guidelines issued by the Inter-Agency Space Debris Coordination Committee (IADC) defined a toroidal Geosynchronous Protected Region, extending 200 km below and above the geosynchronous altitude of 35,786 km, and
Anselmo L, Pardini C
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Improving End-of-Life Communication and Decision-making in Ontario [PDF]

, 2013
Two-page overview of what was learned from a citizen panel on the topic of improving end-of-life communication and decision-making in ...
McMaster Health Forum
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Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Creating space to discuss end-of-life issues in cancer care. [PDF]

Patient Educ Couns, 2019
Cortez D, Maynard DW, Campbell TC.
europepmc   +1 more source