Results 51 to 60 of about 334,167 (212)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Plastic end-to-end treatment of bulbar urethral stricture
GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2013 For bulbar urethral strictures up to 2.5 cm in length, the one-stage urethral plastic surgery with stricture excision and direct end-to-end anastomosis remains the best procedure to guarantee a high success rate.This retrospective review shows the ...
Hamza, Amir +2 more
doaj +1 more source
Effective Emotion Transplantation in an End-to-End Text-to-Speech System
IEEE Access, 2020 In this paper, we propose an effective technique to transplant a source speaker’s emotional expression to a new target speaker’s voice within an end-to-end text-to-speech (TTS) framework.
Young-Sun Joo +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
End-to-end cost assessment of large particle private-wire services
Dianxin kexue, 2016 With the bandwidth of private-wire going up,end-to-end cost assessment of large particle private-wire service becomes more important.Based on the end-to-end bearer form and economic evaluation theory,a cost assessment model was presented,and supplemented
Minfeng ZHANG, Nan ZHOU
doaj +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
PAIN Reports. Introduction:. Pathological levels of methylglyoxal (MG), a reactive dicarbonyl product of glucose, contribute to major neurological complications associated with type II diabetes, including chronic neuropathic pain.
Paramita Basu +8 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Early Outcomes of Aortic Coarctation Repair in Children not Suitable for Percutaneous Catheter Intervention [PDF]
Al-Azhar International Medical JournalBackground: Aortic coarctation (CoA) is a congenital heart disease (CHD) marked by discrete or diffuse narrowing in the descending aorta at the juxta-ductal region.1 It represents 5-8% of all CHD.
Deyaa Aldin Mohamed +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source