Results 191 to 200 of about 7,379,857 (314)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Armoured Amazon female† moths: urticating setae in Notodontidae (Lepidoptera). [PDF]

J Insect Sci
Uemura M, Zalucki MP, Battisti A.
europepmc   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

How to assess ventricular function by fetal echocardiography: expert guidance from the Fetal Heart Society. [PDF]

Ultrasound Obstet Gynecol
Patel SR, Madan N, Eckersley L, Roytman Z, Perez M, Gindes L, Hornberger LK.   +6 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A cloud-edge-end collaborative intelligent caching method based on incremental federated learning algorithms. [PDF]

PLoS One
Huang X, Jin L, Lin K, Wu W, Lin Z.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Middle Meningeal Artery Embolization With n-Butyl Cyanoacrylate in Patients With Chronic Subdural Hematoma: A Randomized Clinical Trial.

JAMA Neurol
Kellner CP, Rai AT, Shoirah H, Srinivasan VM, Gupta R, Starke RM, Al-Mufti F, Matouk CC, Yim B, Fusco MR, Wan J, Liptrap E, Bhuva P, Grandhi R, Cerejo R, Liu JJ, Cherian J, Zhang Q, Kaminsky I, Prestigiacomo CJ, Orru' E, Lin E, Howington J, Evans A, Mehta T, Boo S, Finch I, Liu T, Chitale R, Majidi S, Jankowitz BT, MEMBRANE Study Group.   +31 more
europepmc   +1 more source

Patient-Specific In Silico Prediction of Outcomes of Partial Continuous-Flow LVAD Treatment in Peripartum Cardiomyopathy. [PDF]

Int J Numer Method Biomed Eng
Nagawa J, Sack KL, Nchejane NJ, Motchon YD, Sirry MS, Kraus S, Davies NH, Ntusi NAB, Franz T.   +8 more
europepmc   +1 more source