Results 121 to 130 of about 3,009,219 (314)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

End-Capping Reaction of Living Anionic Poly(benzyl methacrylate) with a Pentafluorophenyl Ester for a Norbornenyl-ω-End Macromonomer with a Long Flexible Spacer: Advantage in the Well-Controlled Synthesis of Ultrahigh-Molecular-Weight Bottlebrush Polymers

, 2019
12-(cis-5-Norbornene-exo-2,3-dicarboximido)­dodecanoate pentafluorophenyl ester (exo-NBC12-PFP) was used as a norbornene-substituted end-capping terminator of living anionic polymers.
Ho-Bin Seo (1836742), Zuwang Wen (6862709), Jae-Suk Lee (1468576), Myung-Jin Kim (1700782), Yong-Guen Yu (2064445), Chang-Geun Chae (1810498)   +5 more
core   +1 more source

Conditions for Open-Ended Evolution in Immigration Games

CoRR, 2020
The Immigration Game (invented by Don Woods in 1971) extends the solitaire Game of Life (invented by John Conway in 1970) to enable two-player competition. The Immigration Game can be used in a model of evolution by natural selection, where fitness is measured with competitions.
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Types of submarine pipeline boundary conditions and implications for pipeline walking behaviour [PDF]

Journal of Hebei University of Science and Technology
The ends of deep-sea submarine pipelines are usually connected to wellheads, suspended chain line risers, pipeline end manifolds, etc. , and the boundary conditions at the end of the pipelines are complicated.
Chunhui ZHANG, Wenhao ZHAO, Yinghui TIAN, Le WANG, Hongliang YUE, Hongyu SHE, Mingjie SONG   +6 more
doaj   +1 more source

Interaction curves for vibration and buckling of thin-walled composite box beams under axial loads and end moments

, 2010
Interaction curves for vibration and buckling of thin-walled composite box beams with arbitrary lay-ups under constant axial loads and equal end moments are presented.
Lee, Jaehong, Vo, Thuc
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Flexural strengthening of reinforced concrete beams using external steel elements with different end conditions

Open Engineering
Strengthening of reinforced concrete (RC) beams has been an important focus due to deterioration, strength degradation, code compliance, change of use, and increased loading demands over time.
Khan Bilal, Gul Akhtar, El Hachem Chady, Shahzada Khan, Saeed Salman, Azab Marc   +5 more
doaj   +1 more source

Hydroclimatic differences over the past 2300 years in arid Central Asia and their potential impacts on human activities revealed by End Member Modelling Analysis of lake sediments

Quaternary Science Advances
The arid Central Asia (ACA) is highly sensitive to global changes, making it critical for climate and environmental change research. Previous studies have demonstrated that the ACA experienced different hydroclimatic conditions during the late Holocene ...
Yingying Wei, Kang'en Zhou, En'guo Sheng, Bin Liu, Jianghu Lan   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source