Results 131 to 140 of about 3,009,219 (314)
WANDA: an end-to-end solution for tele-monitoring of chronic conditions
International Journal of Integrated Care, 2012 Majid Sarrafzadeh, Richard Sykes
doaj +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
End conditions for interpolatory quintic splines
, 1980 Accurate end conditions are derived for quintic spline interpolation at equally spaced knots. These conditions are in terms of available function values at the knots and lead to 0(h6) covergence uniformly on the interval of ...
Papamichael, N, Behforooz, GH
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Numerical Vibration Analysis of Rectangular Beams for Different End Conditions
, 2016 In this study the vibration behaviour of rectangular beams with different end conditions i.e. for simply supported and cantilever type is determined. This behaviour is estimated for two different materials namely aluminum (Al6063L) and mild steel (304L).
, Thota Nithin Prabhakar, Dommeti Vamsi Krishna
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
End-of-Life Issues and Support Needs of People with Profound Intellectual and Multiple Disability
, 2022 Throughout life people with profound intellectual and multiple disability (PIMD) are likely to experience multiple complex and life-threatening conditions, creating a need for decision-making about end-of-life care and support.
H Voss (7717808) +2 more
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Journal of Long-Term Care, 2019 Context: Globally, populations are ageing, with people increasingly likely to die with chronic progressive illness. In this context, there is widespread interest in advance care planning (ACP), where people are supported to think about and express ...
Josie Dixon, Martin Knapp
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
, 2006 End of project reportThis project set out to identify soil properties that most influence grassland production under low mineral nitrogen input conditions. Sixteen farms were selected in Counties Limerick and Clare and the soil sampled. Soil physical and
Culleton, Noel +3 more
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