Results 41 to 50 of about 1,611,302 (259)

Experimental Study of a Relatively Week Density Jump on [PDF]

open access: yesمهندسی منابع آب, 2009
Management of the density jumps in lakes and reservoirs plays an important role in the water quality improvement and in the sediment deposition and erosion management.
N B, A SH, M GH
doaj  

Influence of span/depth ratio on the measurement of mode II fracture toughness of wood by end-notched flexure test

open access: yesJournal of Wood Science, 2001
The influence of the span/depth ratio when measuring the mode II fracture toughness of wood by endnotched flexure (ENF) tests was examined. Western hemlock (Tsuga heterophylla Sarg.) was used for the specimens. The ENF tests were conducted by varying the span/depth ratios; and the fracture toughness at the beginning of crack propagation GIIc was ...
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

A novel cooperative opportunistic routing scheme for underwater sensor networks [PDF]

open access: yes, 2016
Increasing attention has recently been devoted to underwater sensor networks (UWSNs) because of their capabilities in the ocean monitoring and resource discovery.
Abello   +8 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Hydraulic Parameters and Morphometric Variables Interactions in Bedrock Channel

open access: yesQuaestiones Geographicae, 2016
Present study is on the interdependent nature of hydraulic parameters and morphometric variables of a bedrock river. In this study, using dumpy level, GPS, satellite images and some mathematical equations a data set on hydraulics and morphometric ...
Biswas Biswajit, Chandra Das Balai
doaj   +1 more source

XPS study of the chemical structure of the nickel/silicon interface [PDF]

open access: yes, 1980
The chemical nature of the Ni/Si, Ni/Ni_(2)Si and Si/Ni_(2)Si interfaces have been investigated using x‐ray photoelectron spectroscopy. Peak position, line shapes, and envelope intensities are used to probe the compositional structure of these systems ...
Grunthaner, F. J.   +2 more
core   +1 more source

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