Results 51 to 60 of about 1,611,302 (259)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Experimental Study of Reactive Powder Reinforced Concrete Beams Strengthened with CFRP for Critical Shear Zones [PDF]

open access: yesEngineering and Technology Journal, 2015
The behavior and shear strength characteristics of eight SFRHSC beams strengthened with CFRP strips subjected to combined bending and shear are studied in the present research (in addition to a 9th control beam without CFRP strengthening).
Alaa M. Al-Habbobi   +2 more
doaj   +1 more source

Hydrodynamic forces on submerged floating tube: The effect of curvature radius and depth level

open access: yesKapal, 2022
The discussion of hydrodynamic forces becomes an important issue in determining the dynamic behavior of the Submerged Floating Tunnel Bridge (SFTB) structure.
Jamiatul Akmal   +6 more
doaj   +1 more source

Hubble Space Telescope Pixel Analysis of the Interacting Face-on Spiral Galaxy NGC 5194 (M51A)

open access: yes, 2011
A pixel analysis is carried out on the interacting face-on spiral galaxy NGC 5194 (M51A), using the HST/ACS images in the F435W, F555W and F814W (BVI) bands.
Chang Hee Ree   +32 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Green Communication for Underwater Wireless Sensor Networks: Triangle Metric Based Multi-Layered Routing Protocol

open access: yesSensors, 2020
In this paper, we propose a non-localization routing protocol for underwater wireless sensor networks (UWSNs), namely, the triangle metric based multi-layered routing protocol (TM2RP).
Ahmad M. Khasawneh   +8 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Experimental and numerical study on scratching test [PDF]

open access: yes, 2013
This paper presents recent investigation of the material removal mechanism in single grit grinding test. Single grit scratches were generated experimentally by using CBN grit on En24T steel and compared with numerical simulation by using finite element ...
Chen, Xun, Öpöz, Tahsin
core  

The $(h,k)$-Server Problem on Bounded Depth Trees

open access: yes, 2017
We study the $k$-server problem in the resource augmentation setting i.e., when the performance of the online algorithm with $k$ servers is compared to the offline optimal solution with $h \leq k$ servers.
Bansal, Nikhil   +3 more
core   +1 more source

Determining the contribution of volcanic ash and boundary layer aerosol in backscatter lidar returns: a three‐component atmosphere approach [PDF]

open access: yes, 2011
A solution of the lidar equation is discussed, that permits combining backscatter and depolarization measurements to quantitatively distinguish two different aerosol types with different depolarization properties.
Hogan, Robin, Marenco, Franco
core   +1 more source

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