Results 111 to 120 of about 189,790,258 (290)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Correction to: Economic evaluation of patient costs associated with tuberculosis diagnosis and care in Solomon Islands

BMC Public Health, 2021
Kerri Viney, Noel Itogo, Takuya Yamanaka, Ridha Jebeniani, Anupama Hazarika, Fukushi Morishita, Nobuyuki Nishikiori, Susana Vaz Nery   +7 more
doaj   +1 more source

Coronavirus at the end of the world: Antarctica matters. [PDF]

Soc Sci Humanit Open, 2020
Frame B, Hemmings AD.
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Female Brazilian Diaspora during The End of the World: Decolonial Narratives in Germany and Spain

LL Journal
Las trayectorias personales o repertorios biográficos desempeñan un papel crucial en la configuración del repertorio lingüístico de un individuo. Mi investigación se propone profundizar en este fenómeno dentro de un contexto social, examinando las ...
Miriam Lange
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Apropierea și întârzierea „Parousiei” la părinții ante- și post-niceeni – partea a 2-a [Nearness and Delay of "Parousia" in Pre- and Post-Nicene Fathers – Part 2]

TheoRhēma, 2016
he concepts of the nearness and delay of parusia in the thought of the ante- and post-Nicene Fathers, dealt with in part one, have here been taken up again, this time with a focus on the way the Nicene and post-Nicene Fathers related to the nearness and
Laurențiu Moț
doaj  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Apropierea și întârzierea „Parousiei” la părinții ante- și post-niceeni – partea 1 [Nearness and Delay of "Parousia" in Pre- and Post-Nicene Fathers – Part 1]

TheoRhēma, 2016
Nearness and delay of the parousia for ante and post-Nicene fathers, part one, is an article about how the apostolic and the early Church Fathers perceive the second coming of Jesus in terms of closeness and delay.
Laurențiu Moț
doaj