Results 91 to 100 of about 189,790,258 (290)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Environment Matters at the World Bank, 2009 Annual Review : Banking on Biodiversity [PDF]

open access: yes, 2010
This issue of environment matters celebrates the 2010 international year of biodiversity and describes some of the challenges and opportunities in protecting biodiversity for the benefit of humankind. From
World Bank
core   +1 more source

Inumana intertestualità: appunti sulla citazione nelle Poesie della fine del mondo

open access: yesCuadernos de Filología Italiana, 2006
Delfini’s way of writing is often tinged with intertextual quotations or allusions which prove to be functional within his work. In particular, the Poesie della fine del mondo, where the phenomenon acquires a status of unprecedented importance, are ...
Gian Luca Picconi
doaj  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Tanzania at the Turn of the Century : Background Papers and Statistics

open access: yes, 2002
This report is the successor to the Country Economic Memorandum for Tanzania prepared in 1996 (World Bank 1996). The 1996 memorandum focused on the challenge of reforms and paid particular attention to the
World Bank   +1 more
core   +1 more source

Intersecting end of the world branes

open access: yesJournal of High Energy Physics
Dynamical cobordisms implement the swampland cobordism conjecture in the framework of effective field theory, realizing codimension-1 end of the world (ETW) branes as singularities at finite spacetime distance at which scalars diverge to infinite field ...
Roberta Angius   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

China 2030 : Building a Modern, Harmonious, and Creative High-Income Society [pre-publication version]

open access: yes, 2012
China should complete its transition to a market economy--through enterprise, land, labor, and financial sector reforms--strengthen its private sector, open its markets to greater competition and innovation, and ensure equality of opportunity to help ...
Development Research Center of the State Council, P.R.C.   +1 more
core   +1 more source

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