Results 71 to 80 of about 7,085,195 (294)

Descartes on the Infinity of Space vs. Time [PDF]

, 2018
In two rarely discussed passages – from unpublished notes on the Principles of Philosophy and a 1647 letter to Chanut – Descartes argues that the question of the infinite extension of space is importantly different from the infinity of time.
Gorham, Geoffrey
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The End of the World As We Have Known It? An Introduction to Collapsology. [PDF]

Pastoral Psychol, 2022
Bingaman KA.
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The More You Know: Using Knowledge Graphs for Image Classification

, 2017
One characteristic that sets humans apart from modern learning-based computer vision algorithms is the ability to acquire knowledge about the world and use that knowledge to reason about the visual world.
Gupta, Abhinav, Marino, Kenneth, Salakhutdinov, Ruslan   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The end of Ancient World : a historical debate [PDF]

, 2001
With this article, we intend to discuss how some writers since 18th century treated the “decline” of the Roman Empire connected with their historical views.
Ventura da Silva, Gilvan
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Pandemic scientific data sharing recommendations: examining and re-imagining pre-print servers after the end of the world-wide emergency. [PDF]

Antimicrob Steward Healthc Epidemiol, 2023
Doron S, Branch-Elliman W.
europepmc   +1 more source

Large Scale Learning of Agent Rationality in Two-Player Zero-Sum Games

, 2019
With the recent advances in solving large, zero-sum extensive form games, there is a growing interest in the inverse problem of inferring underlying game parameters given only access to agent actions.
Fang, Fei, Kolter, J. Zico, Ling, Chun Kai   +2 more
core   +1 more source