Results 71 to 80 of about 189,790,258 (290)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Development of HARIR (Last Day) Animated Learning Video as Da'wah Media for Grade 6 Elementary School Learning

Magistra
This research aims to develop instructional media in the form of an animated video focused on preaching about the Warning of the Coming of the Last Day, with the hope of providing understanding for sixth-grade elementary school students.
Nur Safitriyanah, Raihan Bisyri Rabbani, Alika Fitara Dwi Permana, Ani Nur Aeni   +3 more
doaj   +1 more source

Poetic images of the end of the world: art, eco-communication and environmental perception [PDF]

Ambiente & Sociedade
Observing which images of climate collapse emerge in young audiences of environmental cinema is the main objective of this article, which fulfills the dual function of relating art to environmental perception and pointing to new paradigms in ...
Ana Silvia Andreu da Fonseca
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Energy End-Use Technologies for the 21st Century. A Report of the World Energy Council [PDF]

, 2004
This report makes clear the opportunities and places technology development firmly centre stage in meeting and overcoming the challenges confronting the energy industry and policy makers.
Schock, R., Larsen, H., Gehl, S., Modlin, R., Morishita, M., Suntola, T., Nakicenovic, N., Haegermark, H.   +7 more
core   +1 more source

The End of the World As We Have Known It? An Introduction to Collapsology. [PDF]

Pastoral Psychol, 2022
Bingaman KA.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The End of World War II

RSA Journal
Sixth contribution to the Forum World War II at 80.
Emily S. Rosenberg
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

World Development Indicators 2005

, 2005
Five years ago the Millennium Declaration recorded the commitment of the members of the United Nations to eliminate poverty and to build a secure and peaceful world conducive to human development.
World Bank
core   +1 more source