Results 61 to 70 of about 11,034,532 (299)

Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD [PDF]

, 2011
Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD) and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome-wide association studies, but the associations of these single nucleotide ...
Kronenberg, F, Fox, Caroline S., Hoffmann, M.M., Powe, Neil, Hwang, Shih-Jen, Siscovick, D.S. (David), W H Kao, Paulweber, Bernhard, Hwang, SJ, Ravi I Thadhani, Rivadeneira Ramirez, F. (Fernando), Carsten A., Böger, Hoffmann, MM, Huang, C., O'Seaghdha, C.M., Kutalik, Z, Köttgen, A., Hoffmann, Michael M., Coassin, S, Heid, Iris M., Hoffmann, Michael M, H.-Erich Wichmann, Witteman, J., Yang, Q. (Qiong Fang), Powe, N., Jacques S Beckmann, Witteman, Jacqueline, Shlipak, M.G. (Michael), Huang, CM, Rettig, Rainer, null null, Heid, I.M. (Iris), Barbara Kollerits, Haun, M., Coassin, S. (Stefan), Krane, V. (Vera), Teumer, A. (Alexander), Hofman, Bert, Powe, N. (Neil), Haun, M, Kronenberg, F. (Florian), Bochud, Murielle, Kutalik, Zoltan, Haak, Thomas, Wichmann, H.E., Kao, W.H.L. (Wen), Wichmann, H.E. (Heinz Erich), Haak, T., Heid, I.M., Siscovick, D, Kronenberg, Florian, Wanner, C, Bochud, M., Krämer, B.K., Hofman, A., Caroline S. Fox, Bernhard K Krämer, Haun, Margot, Carsten A Böger, Wichmann, H-Erich, Kim, Stuart K., Heid, IM, Wichmann, H.-Erich, Wanner, Christoph, Böger, Carsten A., Gorski, M. (Mathias), Boger, CA, Böger, C.A., Krämer, Bernhard K., Coassin, S., Carsten A. Böger, Fox, C.S., Kollerits, B. (Barbara), Michael M. Hoffmann, Gorski, Mathias, Rivadeneira, Fernando, Heid, Iris M, Li, M., Shlipak, M.G., Coassin, Stefan, Kollerits, Barbara, Haak, T. (Thomas), Kollerits, B, David Siscovick, Man Li, Krämer, Bernhard K, Haak, T, Rettig, R, Thomas Haak, Florian Kronenberg, Coresh, J. (Josef), Abbas Dehghan, Zoltán Kutalik, O'Seaghdha, CM, Li, M, Wichmann, HE, Coresh, Josef, Siscovick, David, O'Seaghdha, Conall M., Hoffmann, M.M. (Michael), Wanner, C., O'Seaghdha, C.M. (Conall), Shlipak, MG, Krane, Vera, Chunmei Huang, Hwang, S.J., Stefan Coassin, Rettig, R. (Rainer), Siscovick, D., Shlipak, Michael G, Teumer, Alexander, Gorski, M., Kronenberg, F., Fox, C.S. (Caroline), Fernando Rivadeneira, Jacqueline Witteman, Huang, Chunmei, Paulweber, B., Thadhani, R.I. (Ravi), W. H. Kao, Neil Powe, Kao, W. H., Shih-Jen Hwang, Uitterlinden, Andre, Conall M O'Seaghdha, Li, M. (Man), Beckmann, J.S. (Jacques), Koettgen, Anna, Paulweber, B, Yang, Qiong, Kottgen, A, Yang, Q, Boes, Eva, Huang, C. (Chunmei), Uitterlinden, André; id_orcid, Köttgen, A. (Anna), Powe, N, Fox, CS, Rivadeneira, F., CKDGen Consortium, Boes, E, Boes, E. (Eva), Yang, Q., Beckmann, Jacques S., Ravi I. Thadhani, Murielle Bochud, Michael M Hoffmann, Conall M. O'Seaghdha, Guo Li, Uitterlinden, A.G. (André), Dehghan, A. (Abbas), Hofman, A. (Albert), Witteman, JCM, Böger, C.A. (Carsten), Albert Hofman, Krämer, B.K. (Bernhard), Iris M Heid, Rettig, R., Michael G Shlipak, Dehghan, Abbas, H-Erich Wichmann, Kao, WH, Kraemer, Bernhard K., Köttgen, Anna, Qiong Yang, Josef Coresh, Bochud, M. (Murielle), Michael G. Shlipak, Dehghan, A., Caroline S Fox, O'Seaghdha, Conall M, Shlipak, Michael G., Teumer, A., Iris M. Heid, Coresh, J, Beckmann, Jacques S, Eva Boes, Bernhard Paulweber, Rainer Rettig, Beckmann, J.S., Kao, W.H., Bochud, M, Teumer, A, Wichmann, Heinz-Erich, Jacques S. Beckmann, Boeger, Carsten A., Haun, M. (Margot), Alexander Teumer, André Uitterlinden, Kollerits, B., Uitterlinden, A., Vera Krane, Krane, V, Anna Köttgen, Kutalik, Z., Bernhard K. Krämer, Kramer, BK, Thadhani, R.I., Krane, V., Margot Haun, Thadhani, Ravi I, Li, Guo, Wanner, C. (Christoph), Paulweber, B. (Bernhard), Böger, Carsten A, Hofman, Albert, Christoph Wanner, Li, Man, Mathias Gorski, Li, G., Witteman, J.C.M. (Jacqueline), Thadhani, RI, Beckmann, JS, Gorski, M, Coresh, J., Kutalik, Z. (Zoltán), Thadhani, Ravi I., Boes, E., Li, G (Guo), Fox, Caroline S, Kao, Wen Hong Linda, CKDGen Consortium, [Study group]   +221 more
core   +2 more sources

Life on the list: an exploratory study of the life world of individuals waiting for a kidney transplant

, 2010
Kidney transplantation is the treatment of choice for many individuals with end stage renal disease (ESRD), as transplantation is reported to offer a greater quality of life than renal dialysis.
Long-Sutehall, Tracy, Frankland, Jane, Addington-Hall, Julia, Sque, Magi, Mason, Juan   +4 more
core   +1 more source

Re: Risk of End-Stage Renal Disease Following Live Kidney Donation

Journal of Urological Surgery, 2014
The authors compare the risk of end-stage renal disease (ESRD) in 96217 kidney donors in the United States, followed for a median of 7.6 years with that of a healthy cohort of 20024 nondonors, followed for a median of 15 years of who are at equally low ...
Muzaale AD, Massie AB, Wang MC, Montgomery RA, McBride MA, Wainright JL, Segev DL   +6 more
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Setting reasonable goals for kidney transplant referral among dialysis facilities

BMC Nephrology
Background Determining whether a patient is eligible for kidney transplantation is complex. In this study, we estimate what proportion of patients with end-stage kidney disease (ESKD) might have been suitable candidates for kidney transplantation but ...
Jessica L. Harding, Meredith A. Dixon, Mengyu Di, Julien Hogan, Stephen O. Pastan, Rachel E. Patzer   +5 more
doaj   +1 more source

Shared decision-making and planning end-of-life care for patients with end-stage kidney disease: a protocol for developing and testing a complex intervention

Pilot and Feasibility Studies, 2022
Background Internationally, it has been stressed that advance care planning integrated within kidney services can lead to more patients being involved in decisions for end-of-life care. In Denmark, there is no systematic approach to advance care planning
Louise Engelbrecht Buur, Jeanette Finderup, Henning Søndergaard, Michell Kannegaard, Jens Kristian Madsen, Hilary Louise Bekker   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

End-Stage Kidney Disease following Surgical Management of Kidney Cancer [PDF]

Clinical Journal of the American Society of Nephrology, 2018
We investigated the incidence of ESKD after surgical management of kidney cancer in the Australian state of Queensland, and described patterns in the initiation of kidney replacement therapy resulting from kidney cancer across Australia.All newly diagnosed cases of kidney cancer in the Australian state of Queensland between January of 2009 and December
Ellis, Robert J., Edey, Daniel P., Del Vecchio, Sharon J., McStea, Megan, Campbell, Scott B., Hawley, Carmel M., Johnson, David W., Morais, Christudas, Jordan, Susan J., Francis, Ross S., Wood, Simon T., Gobe, Glenda C.   +11 more
openaire   +5 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies [PDF]

, 2019
Background: Change in albuminuria as a surrogate endpoint for progression of chronic kidney disease is strongly supported by biological plausibility, but empirical evidence to support its validity in epidemiological studies is lacking. We aimed to assess
Chronic Kidney Disease Prognosis Consortium and Chronic Kidney Disease Epidemiology Collaboration
core   +2 more sources