Results 81 to 90 of about 11,034,532 (299)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

A bundled phosphate control intervention (4Ds) for adults with end‐stage kidney disease receiving haemodialysis: A cluster randomized controlled trial

, 2020
AIM: To evaluate the effectiveness of a bundled self-management intervention (taking control of your phosphate with the 4Ds) to improve phosphate control among adults receiving haemodialysis.
Bonner, Ann, Clint Douglas, Milazi, Molly, Ann Bonner, Molly Milazi, Douglas, Clint   +5 more
core   +1 more source

End-stage renal disease and survival in people with diabetes : a national database linkage study [PDF]

, 2014
© The Author 2014. Published by Oxford University Press on behalf of the Association of Physicians. Funding This work was supported by the Wellcome Trust through the Scottish Health Informatics Programme (SHIP).
W. Metcalfe, Conway, B., Bell, S, H. C. Looker, D. Levin, Joss, N., Colhoun, H. M., Sattar, N, McKnight, J, N. Joss, Traynor, J. P., Wild, S.; id_orcid, S. Livingstone, Brady, I, J. P. Traynor, Fletcher, E H, Leese, G., Levin, D, Looker, H C, ?, ?, Lindsay, R. S., Pearson, D., Joss, N, Brady, I., Lindsay, R S, Scottish Diabetes Research Network and Scottish Renal Registry, Colhoun, H M, Wild, S, S. Wild, McKnight, J., B. Conway, Livingstone, S., Sattar, N., J. Mcknight, Traynor, J P, Wild, S., N. Halbesma, Pearson, D, Levin, D., N. Sattar, D. Pearson, Leese, G, Halbesma, N, Halbesma, N., Metcalfe, W, Livingstone, S, Looker, H. C., Bell, S., R. S. Lindsay, Philip, S, I. Brady, S. Bell, G. Leese, Bell, S.; id_orcid, Metcalfe, W., Conway, B, Philip, S., S. Philip, E. H. Fletcher, Fletcher, E. H.   +59 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Assessment of the coding of ESKD in deaths and hospitalisation data: a working paper [PDF]

, 2014
This working paper uses linked data from Western Australia and New South Wales to assess the likelihood that a patient who is hospitalised with end-stage kidney disease (ESKD) will have ESKD recorded on their death record, in order to establish whether ...

core  

Anticoagulation for Atrial Fibrillation in End-stage Kidney Disease

Journal of Controversies in Biomedical Research, 2015
Atrial fibrillation (AF) is the most common arrhythmia in the general population and it has been found to have a higher prevalence in end-stage kidney disease (ESKD).
Gavin Lee, David W Johnson
doaj   +1 more source

Novel coronavirus disease in patients with end‐stage kidney disease

Therapeutic Apheresis and Dialysis, 2020
AbstractThe novel coronavirus disease outbreak started in Wuhan, China, in December 2019 and has since spread rapidly worldwide. As almost all patients with end‐stage kidney disease have been treated with HD in Japan, they have a higher risk of infection than the healthy population. Moreover, the complications of renal failure, such as hypertension and
Shimada, Noriaki, Shimada, Hiroaki, Itaya, Yoshiaki, Tomino, Yasuhiko   +3 more
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Pica in end-stage chronic kidney disease: Literature review

Nefrología (English Edition), 2019
Pica is an individual entity in the patient with chronic kidney disease (CKD), which phenomenon has not been widely studied despite the high reported prevalence.
Claudia N. Orozco-González, Laura Cortés-Sanabria, Roxana M. Márquez-Herrera, Gabriela K. Núñez-Murillo   +3 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source