Results 81 to 90 of about 684,976 (303)

Clinical applications of the Model for End-Stage Liver Disease (MELD) in hepatic medicine

Hepatic Medicine: Evidence and Research, 2013
Tsang Lau, Jawad AhmadDivision of Liver Diseases, Mount Sinai School of Medicine, New York, USAAbstract: The Model for End-Stage Liver Disease (MELD) score incorporates serum bilirubin, creatinine, and the international normalized ratio (INR) into a ...
Lau T, Ahmad J
doaj  

Choosing a pediatric recipient for orthotopic liver transplantation [PDF]

, 1987
Between March 3, 1981, and June 1, 1984, 216 children were evaluated for orthotopic liver transplantation. Of the 216 patients, 117 (55%) had recelved at least one liver transplant by June 1, 1985. Fifty-five (25%) died before transplantation.
Andrew H. Urbach, Atkin, Basil J. Zitelli, Borel, Byar, Byar, Byers W. Shaw, Cox, Cutler, Daniel J. Schaid, Fallon, Gartner, Gartner, Gartner, Gordon, Houssin, Howard Rockette, J. Carlton Gartner, J. Jeffrey Malatack, John Fischer, Lachin, Lee, Mantel, National Institutes of Health Consensus Development Conference statement, Perrin, Sabbeth, Shaw, Shunzaburo Iwatsuki, Starzl, Starzl, Thomas E. Starzl, Zitelli   +31 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Implementation of a living donor liver transplantation program in the Republic of Uzbekistan: a report of the first 40 cases

Clinical Transplantation and Research
Background : Living donor liver transplantation (LDLT) is an effective treatment for patients with end-stage liver disease. This study was performed to evaluate the outcomes of the initial series of LDLT procedures performed in the Republic of Uzbekistan
Konstantin Semash, Timur Dzhanbekov, Mirshavkat Akbarov, Miraziz Mirolimov, Azimjon Usmonov, Navruz Razzokov, Ziyodulla Primov, Temurbek Gaybullaev, Sardor Yigitaliev   +8 more
doaj   +1 more source

Model for End-Stage Liver Disease, Model for Liver Transplantation Survival and Donor Risk Index as predictive models of survival after liver transplantation in 1,006 patients

Clinics, 2015
OBJECTIVES: Liver transplantation has not increased with the number of patients requiring this treatment, increasing deaths among those on the waiting list.
Elisa Maria de Camargo Aranzana, Adriana Zuolo Coppini, Maurício Alves Ribeiro, Paulo Celso Bosco Massarollo, Luiz Arnaldo Szutan, Fabio Gonçalves Ferreira   +5 more
doaj   +1 more source

Liver cirrhosis in England--an observational study: are we measuring its burden occurrence correctly? [PDF]

, 2017
Objectives: Mortality due to liver disease (of which cirrhosis is the end‐stage) is increasing more than any other chronic condition in the UK. This study aims to demonstrate that (i) exclusive reliance on mortality rates may not reveal the true burden ...
Blachier, Bosetti, Campbell, Halliday, Hanley, Jepsen, Jepsen, Leon, Liu, Macgregor, Navaratnam, Ratib, Ratib, Ratib, Roberts, Smith, SriRajaskanthan, von Wulffen, Williams   +18 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Clinical Significance of Serum Adiponectin and Resistin Levels in Liver Cirrhosis

Annals of Hepatology, 2018
Introduction. Adiponectin and resistin levels are increased in patients with cirrhosis, but it prognostic significance is unknown. We sought to investigate the factors associated with adiponectin and resistin levels and its clinical significance in ...
Telma Erotides da Silva, Mariana Costa-Silva, Carina G. Correa, Giovana Denardin, Maria L. Ayres Alencar, Mara S. Pacheco Honório Coelho, Letícia Muraro-Wildner, Maria Luiza-Bazzo, David A. González-Chica, Esther Buzaglo Dantas-Correa, Janaína L. Narciso-Schiavon, Leonardo de Lucca Schiavon   +11 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

New Perspectives on Treatment of Hepatitis B Before and After Liver Transplantation [PDF]

, 2016
open5noThe hepatitis B virus (HBV) infects more than 260 million people globally, with increasing incidence, especially in developing countries.
Bortoluzzi, Ilaria, Burra, Patrizia, Ferrarese, Alberto, Russo, Francesco Paolo, Zanetto, Alberto   +4 more
core   +1 more source