Results 161 to 170 of about 1,257,075 (344)

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

A comparative metabolomic analysis reveals the metabolic variations among cartilage of Kashin-Beck disease and osteoarthritis

open access: yesBone & Joint Research
Aims: The metabolic variations between the cartilage of osteoarthritis (OA) and Kashin-Beck disease (KBD) remain largely unknown. Our study aimed to address this by conducting a comparative analysis of the metabolic profiles present in the cartilage of ...
Hong Chang   +9 more
doaj   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu   +6 more
wiley   +1 more source

Recent Advances in Thalassemia Research: A Comprehensive Assessment From Diagnostic Technologies to Clinical Treatment

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Thalassemia, a common hereditary blood disorder causing impaired globin synthesis and related complications, has seen remarkable progress in recent years due to advancements in genomics and molecular biology. Researchers have identified various gene variants related to thalassemia and improved clinical diagnostic methods, including new genetic testing ...
Chaoqiong Zhou   +7 more
wiley   +1 more source

Large Hydatid Cyst in the Cardiac Interventricular Septum: A Rare Case Report and Literature Review

open access: yesJournal of Clinical Ultrasound, EarlyView.
Hydatid disease is a parasitic disease with a high incidence in pastoral areas in Tibet. The heart is an uncommon location of echinococcosis, and involvement of the interventricular septum is even rarer. This disease can remain asymptomatic for a long time, but may result in cardiac tamponade and sudden death.
Lin Gao, Yixiu Zhang, Xiao Yang
wiley   +1 more source

Dietary recommendations for patients with chronic liver diseases: the need for increased awareness among non-hepatologist physicians

open access: yesBMC Gastroenterology
Background& aim Nutritional awareness is a significant challenge for patients with chronic liver diseases (CLD), especially for those with conditions such as ascites, hepatic encephalopathy, and fatty liver disease. This survey aims to assess nutritional
Yasser Fouad   +8 more
doaj   +1 more source

Attention‐deficit hyperactivity disorder in children and young persons during the COVID‐19 pandemic. A temporal trends analysis of electronic heath records in Greater Manchester, England

open access: yesJCPP Advances, EarlyView.
Abstract Background The incidence of attention‐deficit hyperactivity disorder (ADHD) in children and young people has increased in recent years. Disease frequency varies according to sociodemographic characteristics. There are seasonal patterns in ADHD diagnosis and prescribing with rates falling during school holidays.
Louise Hussey   +7 more
wiley   +1 more source

Pollen Morphology of Crucianella L. (Rubiaceae) Based on Light and Scanning Electron Microscope Data and Implications for Taxonomy

open access: yesMicroscopy Research and Technique, EarlyView.
This study provides the palynological analysis of 12 Crucianella L. taxa using LM and SEM. Variations in pollen size, aperture number, and exine ornamentation were identified as key traits, demonstrating their taxonomic value for distinguishing closely related species and subspecies within the genus. ABSTRACT Crucianella L.
Sevcan Celenk   +3 more
wiley   +1 more source

Tracking the Pulse of the Dunes: Seasonal Metabolic Responses of Liolaemus arambarensis to Climatic Variability

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Seasonal environmental fluctuations profoundly influence ectothermic vertebrates, regulating their physiology, metabolism, and life cycles. This study investigated the metabolic and morphometric seasonal dynamics of the subtropical sand lizard Liolaemus arambarensis, an endangered species endemic to the coastal dunes of southern Brazil.
Artur Antunes Navarro Valgas   +5 more
wiley   +1 more source

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