Results 31 to 40 of about 207,096 (194)

Hepatitis B Virus_Surface Gene Mutations and their Clinical Implications

open access: yesSudan Journal of Medical Sciences, 2017
Hepatitis B infection is a major public health problem caused by hepatitis B virus (HBV). Factors associated with host immunity such as (HBV specific T- and/or B-cell) production and antigen presentation failure and viral determinants such as the HBV ...
Yassir M. Hamadalnil, Sahar Bakheit
doaj   +1 more source

Spatial distribution of Anopheles gambiae sensu lato larvae in the urban environment of Yaoundé, Cameroon

open access: yesInfectious Diseases of Poverty, 2019
Background The rapid and unplanned urbanization of African cities is considered to increase the risk of urban malaria transmission. The present study objective was to assess factors influencing the spatio-temporal distribution of Anopheles gambiae s.l ...
Landre Djamouko-Djonkam   +13 more
doaj   +1 more source

Gut microbiota is associated with bone mineral density: an observational and genome-wide environmental interaction analysis in the UK Biobank cohort

open access: yesBone & Joint Research, 2021
Aims: Despite the interest in the association of gut microbiota with bone health, limited population-based studies of gut microbiota and bone mineral density (BMD) have been made.
Bolun Cheng   +10 more
doaj   +1 more source

TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma

open access: yesJournal of Experimental & Clinical Cancer Research
Background Triggering receptor expressed on myeloid cells 2 (TREM2), a surface receptor predominantly expressed on myeloid cells, is a major hub gene in pathology-induced immune signaling.
Hanrui Guo   +9 more
doaj   +1 more source

Macrophage-mediated delivery of ganciclovir nanocomplexes inhibits the pathogenicity of Kaposi’s sarcoma-associated herpesvirus

open access: yesDiscover Oncology
Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the γ-herpesvirus family, is associated with the development of various malignancies.
Haopeng Tan   +9 more
doaj   +1 more source

When an emerging disease becomes endemic [PDF]

open access: yesScience, 2017
Epidemics, such as HIV in the early 1980s and Ebola in 2014, inspire decisive government investment and action, and individual and societal concern, sometimes bordering on panic. By contrast, endemic diseases, such as HIV in 2017 and tuberculosis, struggle to maintain the same attention.
Graham F. Medley, Anna Vassall
openaire   +2 more sources

Mitochondria-wide association study observed significant interactions of mitochondrial respiratory and the inflammatory in the development of anxiety and depression

open access: yesTranslational Psychiatry, 2023
The aim of this study was to investigate the possible interaction of mitochondrial dysfunction and inflammatory cytokines in the risk of anxiety and depression. We utilized the UK Biobank for the sample of this study.
Li Liu   +14 more
doaj   +1 more source

Dysregulation of Cells Cycle and Apoptosis in Human Induced Pluripotent Stem Cells Chondrocytes Through p53 Pathway by HT-2 Toxin: An in vitro Study

open access: yesFrontiers in Genetics, 2021
Kashin–Beck disease (KBD) mainly damages growth plate of adolescents and is susceptible to both gene and gene–environmental risk factors. HT-2 toxin, which is a primary metabolite of T-2 toxin, was regarded as one of the environmental risk factors of KBD.
Yanan Zhang   +15 more
doaj   +1 more source

DLEU1 promotes cell survival by preventing DYNLL1 degradation in esophageal squamous cell carcinoma

open access: yesJournal of Translational Medicine, 2022
Background Emerging evidence has highlighted the critical roles of long noncoding RNAs (lncRNAs) in tumor development and progression. However, the biological functions and underlying mechanisms of DLEU1 in esophageal squamous cell carcinoma (ESCC ...
Qihang Li   +7 more
doaj   +1 more source

Perception of COVID-19 and Vaccine Acceptance among Healthcare Workers

open access: yesInternational Journal of Microbiology, 2022
Background. COVID-19 infection is more likely to be acquired and transmitted by healthcare workers (HCWs). Furthermore, they serve as role models for communities in terms of COVID-19 vaccination attitudes. As a result, HCWs’ reluctance to vaccinate could
Nader Nemr   +5 more
doaj   +1 more source

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