Results 61 to 70 of about 232,181 (311)
Medico-Legal Update, 2020 A study is conducted to assess the cases of fluoride affected person in selected gram panchayat ,Tonk ,Rajasthan. This study is conducted as perspective to conduct action research after wards. In This study symptoms of fluoride has been categorized in three type of fluorosis skeletal( SKF ),non skeletal fluorosis (NSKF ) and dental fluorosis (DF).In
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A diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles. [PDF]
, 2012 A Diagnostics Platform for the Integrated Mapping, Monitoring, and Surveillance of Neglected Tropical Diseases: Rationale and Target Product ...
Xiao-Nong Zhou (92570) +97 more
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Advanced Science, EarlyView.ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
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Advanced Science, EarlyView.Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth +10 more
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Advanced Science, EarlyView.Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun +11 more
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DLEU1 promotes cell survival by preventing DYNLL1 degradation in esophageal squamous cell carcinoma
Journal of Translational Medicine, 2022 Background Emerging evidence has highlighted the critical roles of long noncoding RNAs (lncRNAs) in tumor development and progression. However, the biological functions and underlying mechanisms of DLEU1 in esophageal squamous cell carcinoma (ESCC ...
Qihang Li +7 more
doaj +1 more source
Trachomatous trichiasis and its management in endemic countries. [PDF]
, 2012 : Trichiasis is the sight-threatening consequence of conjunctival scarring in trachoma, the most common infectious cause of blindness worldwide. Trachomatous trichiasis is the result of multiple infections from childhood with Chlamydia trachomatis, which
Saul N. Rajak +11 more
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Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
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Translational Psychiatry, 2023 The aim of this study was to investigate the possible interaction of mitochondrial dysfunction and inflammatory cytokines in the risk of anxiety and depression. We utilized the UK Biobank for the sample of this study.
Li Liu +14 more
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, 2019 In this chapter, we consider models for disease that may be endemic. In the preceding chapter we studied SIS models with and without demographics and SIR models with demographics. In each model, the basic reproduction number [Formula: see text] determined a threshold. If [Formula: see text] the disease dies out, while if [Formula: see text] the disease
Brauer, Fred +2 more
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