Results 71 to 80 of about 188,726 (292)

Diagnostic accuracy of an automated microscope solution (miLab™) in detecting malaria parasites in symptomatic patients at point-of-care in Sudan: a case–control study

open access: yesMalaria Journal
Background Microscopic detection of malaria parasites is labour-intensive, time-consuming, and expertise-demanding. Moreover, the slide interpretation is highly dependent on the staining technique and the technician’s expertise.
Muzamil M. Abdel Hamid   +10 more
doaj   +1 more source

Secondary Metabolites Composition and Their Histochemical Localization in the Fruit of Piper malgassicum Papini, Palchetti, Gori and Rota Nodari (Piperaceae)

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The anatomy, histochemistry, and secondary metabolite composition were investigated on the drupes of Piper malgassicum, one of the components of the spice voatsiperifery pepper. The high amount of piperine recorded with high‐performance liquid chromatography with photodiode‐array detection analysis was localized with histochemistry mainly ...
Sara Falsini   +11 more
wiley   +1 more source

Nanocomplex hyaluronic acid/ganciclovir@ZIF-8 for ganciclovir efficient delivery and targeted anti-KSHV treatment

open access: yesCancer Nanotechnology
Kaposi's sarcoma-associated herpesvirus (KSHV) infection can cause a variety of tumors and is one of the leading causes of death in acquired immune deficiency syndrome (AIDS) patients. As a small molecule antiviral drug, ganciclovir (GCV) can be used for
Fangling Li   +6 more
doaj   +1 more source

Overexpression of MAP3K3 promotes tumour growth through activation of the NF-κB signalling pathway in ovarian carcinoma

open access: yesScientific Reports, 2019
Mitogen-activated protein kinase kinase kinase 3 (MAP3K3), a member of the serine/threonine protein kinase family, is ubiquitously expressed and acts as an oncogene. However, the expression and exact molecular mechanism of MAP3K3 in ovarian carcinoma (OC)
Ying Zhang   +11 more
doaj   +1 more source

Chemical Composition, Antioxidant, Antimicrobial, Antidiabetic, and Butyrylcholinesterase Inhibitory Activities in Vitro of the Essential Oil and Crude Extracts of the Aerial Parts of Thymus ciliatus

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT This study explores the potential of Thymus ciliatus as a natural source of bioactive compounds by investigating its chemical composition and in vitro biological activities, including antioxidant, antimicrobial, antidiabetic, and anti‐Alzheimer properties.
Nadia Djermane   +8 more
wiley   +1 more source

Mendelian randomization study of the relationship between blood and urine biomarkers and schizophrenia in the UK Biobank cohort

open access: yesCommunications Medicine
Background The identification of suitable biomarkers is of crucial clinical importance for the early diagnosis of treatment-resistant schizophrenia (TRS).
Bolun Cheng   +11 more
doaj   +1 more source

Bioinformatics-based screening of key genes for transformation of liver cirrhosis to hepatocellular carcinoma

open access: yesJournal of Translational Medicine, 2020
Background Hepatocellular carcinoma (HCC) is the most common type of liver tumour, and is closely related to liver cirrhosis. Previous studies have focussed on the pathogenesis of liver cirrhosis developing into HCC, but the molecular mechanism remains ...
Chen Hao Jiang   +17 more
doaj   +1 more source

Volatilome and Antinociceptive Activity of the Traditional Preparation and Compounds from Ageratina grandifolia (Regel) R.M. King & H. Rob.

open access: yesChemistry &Biodiversity, EarlyView.
Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol (4)], tested at 10, 31.6, and 100 mg/kg, intragastrically administered, showed a significant antinociceptive effect in both phases of the formalin test in mice ...
José Alberto Gutiérrez‐González   +5 more
wiley   +1 more source

Brazilian Biomes as Promising Resources of Rhodotorula Yeasts for the Biotechnological Production of Carotenoids

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Yeasts belonging to the genus Rhodotorula are capable of synthesizing carotenoids, such as β‐carotene, γ‐carotene, torulene, torularodine, and astaxanthin. These carotenoids have been shown to offer health benefits to humans, such as immune system strengthening and a reduced risk of chronic degenerative diseases.
David Cristian Rodrigues Lucas   +1 more
wiley   +1 more source

Antiaging, Wound‐Healing Properties and Chemical Characterization of Crude Hydroalcoholic Extract and Fractions of Myrcia neoobscura

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The aim of this study was to characterize the phytochemical profile and potential antiaging and wound‐healing activities of 70% hydroalcoholic crude extract (CHE) from Myrcia neoobscura leaves and its fractions—insoluble (IF), ethyl acetate (EAF), and aqueous (AF)—for use in phytocosmetics for skin application.
Larissa Mascarenhas Krepsky   +17 more
wiley   +1 more source

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