Results 81 to 90 of about 7,309,867 (330)

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

The complete chloroplast genome sequence of Metabriggsia ovalifolia W. T. Wang (Gesneriaceae), a national key protected plant endemic to Karst areas in China

Mitochondrial DNA. Part B. Resources, 2021
Metabriggsia ovalifolia W. T. Wang is one of the first-class national protected plants endemic to Karst areas in China. In this study, the complete chloroplast genome was sequenced using Illumina pair-end sequencing data.
Xiaoling Tian, Hafiz Muhammad Wariss
doaj   +1 more source

Optimal germination methods, ornamental plant features, and ex situ conservation of endemic Campanula grandis Fisch & C.A. Mey

Journal of Environmental Engineering and Landscape Management, 2023
This study aimed to investigate the ornamental utilization, two-year growth performance in natural habitat and cultural conditions, generative production methods, and morphologic and phenologic plant properties of Campanula grandis, which is an endemic ...
Gül Yücel, Kamil Erken
doaj   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

Angewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley, Michael Rust, Moritz Wagner, Ida R. Hipfinger, Paul J. N. Böhm, Cora L. Dieterich, Christopher M. Field, Michael J. Page, Jeremy G. Owen, Robert A. Keyzers, Shinichi Sunagawa, Jörn Piel   +11 more
wiley   +2 more sources

An assessment of the conservation status of a presumed extinct tree species Wendlandia angustifolia Wight ex. Hook.f. in southern Western Ghats, India

Journal of Threatened Taxa, 2020
In this study, we carried out an assessment of IUCN conservation status of Wendlandia angustifolia Wight ex. Hook.f. (Rubiaceae), based on field data on populations and distribution status of this species that is narrowly endemic to southern Western ...
Chellam Muthumperumal, Paramasivam Balasubramanian, Ladan Rasingam   +2 more
doaj   +1 more source

High‐resolution distribution modeling of a threatened short‐range endemic plant informed by edaphic factors

Ecology and Evolution, 2019
Short‐range endemic plants often have edaphic specializations that, with their restricted distributions, expose them to increased risk of anthropogenic extinction.
Sean Tomlinson, Wolfgang Lewandrowski, C. Elliott, B. Miller, S. Turner   +4 more
semanticscholar   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

In Vitro Conditions Research of Sophora koreensis Nakai for Shoot Elongation

Plants
Sophora koreensis Nakai, listed as endangered on the IUCN Red List, is a species native to Korea, specifically found in parts of Gangwon-do. Recent research highlights its potential in hangover relief and as an antioxidant source, sparking interest in ...
Hwa Lee, Gyu Il Han, Kyeong-Seong Cheon, Eun Ju Cheong   +3 more
doaj   +1 more source

Voluntary Collective Action to Address Growing Agricultural Challenges in Two Countries: Experimental Insights and Commonalities

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT We conducted two framed field economic experiments with citrus farmers in Florida, United States and soybean farmers in Argentina to investigate their willingness to coordinate pest and weed management efforts. Despite the contrast between these two agricultural contexts, we find striking behavioral commonalities.
Ariel Singerman, Sergio H. Lence
wiley   +1 more source