Results 41 to 50 of about 2,888,509 (300)

Case Report: Hydatid Disease as a Potential Cause of Leukocytoclastic Vasculitis in Endemic Regions [PDF]

Leukocytoclastic vasculitis (LCV) is a type of vasculitis that affects small vessels and is commonly associated with infections, malignancies, drugs, and autoimmune diseases. In this case, a 75-year-old female patient presented with clinical signs of LCV,
Feyza Nur Akın Birincioğlu, Zeynep Beyza Konyalıoğlu, Gamze Kılıç, Konyalıoğlu, Zeynep Beyza, Akın Birincioğlu, Feyza Nur, KILIÇ, GAMZE   +5 more
core   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Assessment of the Influence of Climatic Factors on the Incidence of Crimean Hemorrhagic Fever: a Comprehensive Analysis of Data for Russia, Kazakhstan, Turkey and Iran between 1999 and 2022

Проблемы особо опасных инфекций
In recent decades, the epidemiology of vector-borne infectious diseases has changed significantly due to global warming, which affects the habitats of vectors and increases the rate of spread of pathogens.
I. A. Lizinfeld, N. Yu. Pshenichnaya, E. V. Naidenova, G. A. Gurkin, K. D. Blinova, G. N. Abuova, H. Leblebicioglu, M. Mardani, V. G. Akimkin   +8 more
doaj   +1 more source

Canine heartworm disease (Dirofilaria immitis) in Western Europe: survey of veterinary awareness and perceptions

Parasites & Vectors, 2014
Background This survey examines the experience and opinion of veterinarians with canine heartworm (HW; Dirofilaria immitis) infection in non-endemic and endemic areas of Europe.
Claudio Genchi, Dwight Bowman, Jason Drake   +2 more
doaj   +1 more source

The endemic flora of Morocco

, 2013
Morocco is characterized by high vascular plant diversity with an estimated 4200 species and subspecies of which 22% are endemic. This study presents an updated list of the endemic species in the Moroccan flora following the classification of APG III ...
Rankou, Hassan, Christenhusz, Maarten J. M., Culham, Alastair, Jury, Stephen L., Lhomme, Patrick   +4 more
core   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

Analysis and Forecast of the Spread of Particularly Dangerous Mycoses around the World

Проблемы особо опасных инфекций
The literature review presents an analysis of publications over the past five years on the global distribution of particularly dangerous (endemic) mycoses: coccidioidomycosis, histoplasmosis, blastomycosis, paracoccidioidomycosis. The causative agents of
A. V. Lipnitsky, N. V. Polovets, A. A. Murugova, A. V. Toporkov   +3 more
doaj   +1 more source

Endemic regions located in the south of Bénin (data source: PNLLUB, 2016 report).

, 2018
The five most endemic regions are located around the Ouèmè river (A); Ouinhi is one of the most endemic regions, showing the higher percentage of Category III cases (B).
Inès Elvire Agbo (4952020), Arnaud Setondji Amoussouhoui (3159873), Ghislain Emmanuel Sopoh (245747), Roch Christian Johnson (245759), Mark Nichter (727792), Anita Carolle Wadagni (4925833), Micah Boyer (3159879), Paulin Aoulou (3159870), Jean-Gabin Houezo (3159876)   +8 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source