Results 51 to 60 of about 2,888,509 (300)

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

Angewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley, Michael Rust, Moritz Wagner, Ida R. Hipfinger, Paul J. N. Böhm, Cora L. Dieterich, Christopher M. Field, Michael J. Page, Jeremy G. Owen, Robert A. Keyzers, Shinichi Sunagawa, Jörn Piel   +11 more
wiley   +2 more sources

LLM‐Assisted Design of Ultralow‐κ$\kappa$ Chalcogenides

Advanced Science, EarlyView.
An AI assisted, physics guided workflow accelerates the discovery of ultralow thermal conductivity materials by combining Bayesian optimization, evidence conditioned LLM reasoning, and automated physics‐based validation. The framework uncovers dynamically stable Ag based chalcogenides with ultralow thermal conductivity and promising thermoelectric ...
Yujie Liu, Congran Jia, Yuzhou Hao, Xuejie Li, Yang Wang, Artem Oganov, Jun Sun, Xiangdong Ding, Turab Lookman, Zhibin Gao   +9 more
wiley   +1 more source

The Incidence and Trends of Yellow Fever from 1990 to 2021 in Major Endemic Regions: A Systematic Analysis Based on the 2021 Global Burden of Disease Study

Pathogens
As a re-emerging disease, the worldwide burden and trends of yellow fever (YF) remain inadequately quantified. This study aims to assess the incidence of YF both globally and in major endemic regions from 1990 to 2021.
Xinwei Wang, Bin Li, Baoren He, Xipeng Yan, Linbin Huang, Jinlian Li, Rongji Lai, Mingshuang Lai, He Xie, Qiuhong Mo, Limin Chen   +10 more
doaj   +1 more source

Close encounters of three kinds: Case-based report of endemic mycoses in the environs of New York city

Respiratory Medicine Case Reports, 2020
The term “endemic mycoses” refers to a group of fungi that maintains a baseline rate of infection only in certain geographical regions due to the hospitable enviormental conditions these regions offer.
Ravi Manglani, MD, Helena Tomac Pavosevic, MD, Liying Han, MD, PhD, Oleg Epelbaum, MD   +3 more
doaj   +1 more source

Airports in List of Top 100 Destination Risk located in non-endemic regions.

, 2013
Airports in List of Top 100 Destination Risk located in non-endemic regions.
Lauren Gardner (451915), Sahotra Sarkar (78681)   +1 more
core   +1 more source

Gapless Complete Genome and Multi‐Omics Illuminate Immune Adaptation and Host‐Virus Interactions in a Coronavirus Reservoir

Advanced Science, EarlyView.
We present a complete T2T genome assembly for a key bat reservoir. Integrating population genomics, comparative genomics, transcriptomics, single‐cell omics, and functional assays, we resolve previously inaccessible genomic regions and identify evolutionary signatures associated with immune adaptation.
Yuting Wang, Sheng Zhang, Linxia Ouyang, Xin Du, Xin Huang, Zhilin Wang, Huixian Xie, Jiale Tang, Liyi Lou, Wenqing Ling, Weihao Wang, Jiang Zhou, Zhen Liu, Yibo Hu, Fuwen Wei, Guangping Huang   +15 more
wiley   +1 more source

Rheumatic Heart Disease in Europe: Insights from a Pilot Screening Study and a Scoping Review

Global Heart
Background: Rheumatic heart disease (RHD) remains a preventable cause of cardiovascular morbidity/mortality, disproportionately affecting socioeconomically disadvantaged populations. While largely controlled in high-income countries, RHD persists in low-
Martina Steinmaurer, Lea Baertz, Taariq Salie, Shekhar Saha, Dominik Joskowiak, Ulrich Seybold, Eimo Martens, Joselyn Rwebembera, Christian Hagl, Mark Engel   +9 more
doaj   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Isolated prostate tuberculosis: A rare condition

Urology Case Reports
Tuberculosis remains a global health threat, notably with a considerable burden of extrapulmonary cases. Prostate tuberculosis stands out as a rare and challenging diagnosis, often resulting in substantial management delays.
Omar Bellouki, Abdelmounim Boughaleb, Ilyas Soufiani, Imad Boualaoui, Hachem El Sayegh, Yassine Nouini   +5 more
doaj   +1 more source

Number of LF and STH co-endemic countries within WHO regions.

, 2016
Number of LF and STH co-endemic countries within WHO regions.
Alexei Mikhailov (663944), Antonio Montresor (217485), Jonathan King (373906), Denise Mupfasoni (259815)   +3 more
core   +1 more source