Results 131 to 140 of about 187,490 (264)

The complete Chloroplast Genome of <i>Dianthus Helenae</i>, an Endemic Species with Medicinal Potential from the Nuratau Mountains, Uzbekistan. [PDF]

F1000Res
Ergashov I, Mingboev F, Rasulov F, Hamrayev D, Sultonov D, Achilova R, Xaydarov S, Khujamkulov B, Utayeva F, Jabborova O, Yusupov Z.   +10 more
europepmc   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Complete chloroplast genome of the endemic species <i>Hoya lockii</i> (Apocynaceae) from Viet Nam. [PDF]

Mitochondrial DNA B Resour
Nguyen NTT, Lee C, Yongsa M, Nguyen QH, Jo S, Sy TD, Chu MH.   +6 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Multi-Omics Reveal Haplotype-Specific BGC Divergence and Organ-Specific Iridoid Glycoside Accumulation in Endemic Species Rehmannia chingii. [PDF]

Physiol Plant
Zhang W, Han Y, Jin X, Guo K, Jia X, Wang H, Bai F, Bai H, Li P, Du W, Jiang Y, Zhu S, Zhang Y.   +12 more
europepmc   +1 more source

On the Global Asymptotic Stability of an Infection‐Age‐Structured Competitive Model

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We investigate an infection‐age‐structured competitive epidemiological model involving multiple strains. While classical results establish competitive exclusion when a unique maximal basic reproduction number exists, we provide here a complete characterization of the asymptotic behavior for an arbitrary number of populations without assuming ...
S. Girel, Q. Richard
wiley   +1 more source

Comparative Chloroplast Genomics of <i>Cousinia</i> (Asteraceae) With Nine Newly Sequenced Endemic Species From Central Asia. [PDF]

Ecol Evol
Karimov B, Hamrayev D, Esanov H, Eshonkulov A, Omonov O, Boboyeva N, Karimova D, Umedov A, Asatulloev T, Yusupov Z, Tojibaev KS.   +10 more
europepmc   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Prediction of Suitable Habitats for <i>Bisetocreagris</i> (Pseudoscorpiones: Neobisiidae) in China and Its Application in Conserving Endemic Species Diversity. [PDF]

Ecol Evol
Liu S, Li Y, Xie F, Li Y, Wei Z, Yang D, Shi A.   +6 more
europepmc   +1 more source

Macro‐ and micromorphological insights into Iranian Onobrychis subgenus Onobrychis Miller (Fabaceae): exploring fruit traits for taxonomic clarity

Nordic Journal of Botany, EarlyView.
This study provides a comprehensive examination of fruit morphology and micromorphology characteristics of 28 populations of Onobrychis subgenus Onobrychis taxa from Iran, using both light and scanning electron microscopy. For each trait, 25 replicates were analyzed, encompassing a wide range of qualitative and quantitative traits.
Seyed Mehdi Talebi, Narjes Azizi, Raheleh Tabaripour   +2 more
wiley   +1 more source