Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer [PDF]
, 2018 Background Endocrine therapies are the mainstay of treatment for oestrogen receptor (ER)-positive (ER+) breast cancer (BC). However, resistance remains problematic largely due to enhanced cross-talk between ER and growth factor pathways, circumventing ...
A Carracedo +43 more
core +6 more sources
Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
, 2017 Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core +2 more sources
Common endocrine disorders associated with the polycystic ovary syndrome
Menopause Review, 2021 Ibrahim Abdelazim +2 more
doaj +1 more source
Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]
, 1988 We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M. +3 more
core +1 more source
Medicine, 2013 Abstract A biochemical investigation consists of three phases: (i) pre-analytical, in which the sample is taken in an appropriate manner; (ii) analytical, in which the analyte concentration is estimated; and (iii) post-analytical, in which the result is interpreted.
David Halsall +3 more
openaire +2 more sources
A Brand-new Research Method of Neuroendocrine System [PDF]
arXiv, 2007 In this paper, we present the empirical investigation results on the neuroendocrine system by bipartite graphs. This neuroendocrine network model can describe the structural characteristic of neuroendocrine system. The act degree distribution and cumulate act degree distribution show so-called shifted power law-SPL function forms.
arxiv
Rapid bioconcentration of steroids in the plasma of three-spined stickleback Gasterosteus aculeatus exposed to waterborne testosterone and 17β-oestradiol [PDF]
, 2007 The relationship over time between the concentrations of two steroids, singly and in combination, in a static exposure system and in the blood of three-spined stickleback Gasterosteus aculeatus, held within the exposure system was investigated. Groups of
Matthiessen, P. +3 more
core +1 more source
Space nutrition: the key role of nutrition in human space flight [PDF]
arXiv, 2016 From the basic impact of nutrient intake on health maintenance to the psychosocial benefits of mealtime, great advancements in nutritional sciences for support of human space travel have occurred over the past 60 years. Nutrition in space has many areas of impact, including provision of required nutrients and maintenance of endocrine, immune, and ...
arxiv
Beneficial effects of intercellular interactions between pancreatic islet cells in blood glucose regulation [PDF]
, 2009 Glucose homeostasis is controlled by the islets of Langerhans which are equipped with alpha-cells increasing the blood glucose level, beta-cells decreasing it, and delta-cells the precise role of which still needs identifying. Although intercellular communications between these endocrine cells have recently been observed, their roles in glucose ...
arxiv +1 more source
Follicular and endocrine dose responses according to anti-Müllerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049) [PDF]
, 2015 Objective: To study the association between serum anti-Mullerian hormone (AMH) levels and follicular development and endocrine responses induced by increasing doses (5.2-12.1 mu g/day) of a novel recombinant human FSH (rhFSH, FE 999049) in patients ...
Andersen, Anders Nyboe +9 more
core +2 more sources