Results 81 to 90 of about 858,546 (315)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
, 2013 Despite the high prevalence of performance-enhancing drug (PED) use, media attention has focused almost entirely on PED use by elite athletes to illicitly gain a competitive advantage in sports, and not on the health risks of PEDs.
Bhasin, Shalender +11 more
core +1 more source
Correlation Analysis of Serum TYROBP Level and Metabolic Indexes of Obesity
Diabetes, Metabolic Syndrome and ObesityZhaohui Xiao, Guiyan Han, Yu Gao, Guifen Li, Jianqiu He, Hongli Li, Xiaoyan Liu, Jie Wang, Chen Yang Endocrinology Department, Affiliated Hospital of Chengde Medical College, Chengde, People’s Republic of ChinaCorrespondence: Guiyan Han, Email 1486984873@
Xiao Z +8 more
doaj
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Common endocrine disorders associated with the polycystic ovary syndrome
Menopause Review, 2021 Ibrahim Abdelazim +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Physiology of Endocrine System and Related Metabolic Disorders
, 2021 Endocrine system is comprised of multiple glands. All of these glands secrete different hormones into the body. Most of the body’s functions, i.e., metabolism, growth, development, electrolyte balance, and reproduction, are regulated by these endocrine ...
Khan, Ajab +5 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Endocrine aspects of cancer gene therapy [PDF]
, 2004 The field of cancer gene therapy is in continuous expansion, and technology is quickly moving ahead as far as gene targeting and regulation of gene expression are concerned.
BOSCARO, MARCO +2 more
core +1 more source