Results 121 to 130 of about 858,546 (315)
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Contamination of Endocrine Disrupting Compounds in Environment [PDF]
, 2010 Endocrine disrupting compounds (EDCs) are the substances that disrupt normal functions of hormones produced by endocrine glands affecting to system and organism functions under hormone control altering from nature conditions, consequently cause adverse ...
วิเศษมณี, วรางคณา
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Frontiers in EndocrinologyBackgroundIn recent years, with the widespread use of immune checkpoint inhibitors (ICIs) in cancer treatment, the toxicity associated with immunotherapy of ICIs has attracted more attention from scholars.
Jun Zhao +5 more
doaj +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Endocrine complications of cancer immunotherapy
, 2018 Immunotherapy using monoclonal antibodies — checkpoint inhibitors — is a dynamically evolving discipline of clinical oncology and a new hope for patients with advanced and disseminated cancer. However, the activation of T-lymphocytes can at the same time
Jarząb, Barbara; Department of Nuclear Medicine and Endocrine Oncology, Maria Skłodowska-Curie Institute — Oncology Centre, Gliwice Branch, Gliwice, Poland +2 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Construction of predictive model for programmed death-1 inhibitor-related endocrine adverse events
Zhongguo Linchuang YixueObjectiveTo identify the independent predictors of programmed death-1 (PD-1) inhibitor-related endocrine adverse events and construct a clinically usable risk prediction model. MethodsA total of 302 patients with solid tumors treated with PD-1 inhibitors
Jiaying SHI +7 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
The role of liver-derived insulin-like growth factor-I
, 2009 IGF-I is expressed in virtually every tissue of the body, but with much higher expression in the liver than in any other tissue. Studies using mice with liver-specific IGF-I knockout have demonstrated that liver-derived IGF-I, constituting a major part ...
Ohlsson, Claes, +7 more
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