Results 121 to 130 of about 991,500 (305)

In vitro endocrine activity of mycotoxins and their mixtures.

, 2015
A lot of substances in food and feed can interfere with the hormonal system of humans and animals by influencing the synthesis, metabolism or transport of hormones; or by interacting directly with the hormone receptor (as an agonist or antagonist).
L. Pussemier, A. Evrard, K. Vandermeiren, A. Callebaut, H. Demaegdt   +4 more
core  

Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement

, 2013
Despite the high prevalence of performance-enhancing drug (PED) use, media attention has focused almost entirely on PED use by elite athletes to illicitly gain a competitive advantage in sports, and not on the health risks of PEDs.
Bhasin, Shalender, Nyberg, Fred,, Fred Nyberg, Larry Bowers, Wood, Ruth I., Bowers, Larry, Ruth I. Wood, Harrison G. Pope, Shalender Bhasin, Alan Rogol, Pope, Harrison G., Jr., Rogol, Alan   +11 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Endocrine tumours of the pancreas

, 2000
Endocrine tumours of the pancreas, also known as islet cell tumours, are neuroendocrine tumours arising from the pancreatic islets. Pancreatic endocrine tumours are uncommon and no endocrine surgeon has vast experience with them. Patients with these rare
Fan, ST, Lo, CY
core   +1 more source

Construction of predictive model for programmed death-1 inhibitor-related endocrine adverse events

Zhongguo Linchuang Yixue
ObjectiveTo identify the independent predictors of programmed death-1 (PD-1) inhibitor-related endocrine adverse events and construct a clinically usable risk prediction model. MethodsA total of 302 patients with solid tumors treated with PD-1 inhibitors
Jiaying SHI, Wei WEI, Ting HAN, Xiao ZHOU, Meng ZHUO, Xiaolin LIN, Tao TAO, Xiuying XIAO   +7 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Editorial: Cardiorenal dysregulation in endocrine disorders: innovative mechanisms and therapeutic interventions

Frontiers in Pharmacology, 2023
Noha M. Shawky, Eman Soliman, Eman Soliman, Abdel A. Abdel-Rahman, Samar Rezq, Samar Rezq   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Association of Endocrine Conditions With Takotsubo Cardiomyopathy: A Comprehensive Review

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Sonali Gupta, Pradeep Goyal, Sana Idrees, Sourabh Aggarwal, Divyansh Bajaj, Joseph Mattana   +5 more
doaj   +1 more source

Mapping Organism-wide Single Cell mRNA Expression Linked to Extracellular Vesicle Biogenesis, Secretion, and Cargo

Function
Extracellular vesicles (EVs) are functional lipid-bound nanoparticles trafficked between cells and found in every biofluid. It is widely claimed that EVs can be secreted by every cell, but the quantity and composition of these EVs can differ greatly ...
Thomas J LaRocca, Daniel S Lark
doaj   +1 more source