Results 121 to 130 of about 926,453 (300)

Construction of predictive model for programmed death-1 inhibitor-related endocrine adverse events

Zhongguo Linchuang Yixue
ObjectiveTo identify the independent predictors of programmed death-1 (PD-1) inhibitor-related endocrine adverse events and construct a clinically usable risk prediction model. MethodsA total of 302 patients with solid tumors treated with PD-1 inhibitors
Jiaying SHI, Wei WEI, Ting HAN, Xiao ZHOU, Meng ZHUO, Xiaolin LIN, Tao TAO, Xiuying XIAO   +7 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Editorial: Cardiorenal dysregulation in endocrine disorders: innovative mechanisms and therapeutic interventions

Frontiers in Pharmacology, 2023
Noha M. Shawky, Eman Soliman, Eman Soliman, Abdel A. Abdel-Rahman, Samar Rezq, Samar Rezq   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Antiserum directed against chromogranin A and B (CAB) is a useful marker for peptide hormone-producing endocrine cells and tumors

, 1992
Certain proteins, such as the chromogranins, have a ubiquitous occurrence in nearly ail peptide hormone-producing cells. To date, little is known about their functional role as structural proteins, precursors of bioactive peptides, or enzymes.
Håkansson, R, Eriksson, Barbro,, Alumets, J, Öberg, Kjell,, Sundler, F, Larsson, L, Lundqvist, G   +6 more
core   +1 more source

Association of Endocrine Conditions With Takotsubo Cardiomyopathy: A Comprehensive Review

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Sonali Gupta, Pradeep Goyal, Sana Idrees, Sourabh Aggarwal, Divyansh Bajaj, Joseph Mattana   +5 more
doaj   +1 more source

Mapping Organism-wide Single Cell mRNA Expression Linked to Extracellular Vesicle Biogenesis, Secretion, and Cargo

Function
Extracellular vesicles (EVs) are functional lipid-bound nanoparticles trafficked between cells and found in every biofluid. It is widely claimed that EVs can be secreted by every cell, but the quantity and composition of these EVs can differ greatly ...
Thomas J LaRocca, Daniel S Lark
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Pharmacological management of endocrine emergencies

The symptoms and signs of endocrine crises overlap with those of other severe disease states, so all doctors should have a basic understanding of all of them.
Ben Shabath , Yael
core  

Hematological Malignancy in a Hypophysectomised Acromegalic Patient Under 4-Year Therapy with Somatostatin Analogues: From a Rib Lump Underlying Bone Plasmatocytoma Features to Multiple Myeloma

Diagnostics
Acromegaly is associated with a higher risk of certain malignancies, but not hematological neoplasia, although multiple myeloma (MM) was found in very limited cases.
Mihaela Stanciu, Alina Cătană, Ruxandra Paula Ristea, Denisa Tanasescu, Mara Carsote, Florina Ligia Popa, Ioana-Codruța Lebădă   +6 more
doaj   +1 more source