Results 81 to 90 of about 1,087,207 (293)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Indian Journal of Medical and Paediatric Oncology, 2020 Aims: To determine the prevalence and severity of endocrine and metabolic derangements in childhood-onset ALL survivors from Thailand and to describe the associated risk factors.
Chansuda Bongsebandhu-phubhakdi +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Correlation Analysis of Serum TYROBP Level and Metabolic Indexes of Obesity
Diabetes, Metabolic Syndrome and ObesityZhaohui Xiao, Guiyan Han, Yu Gao, Guifen Li, Jianqiu He, Hongli Li, Xiaoyan Liu, Jie Wang, Chen Yang Endocrinology Department, Affiliated Hospital of Chengde Medical College, Chengde, People’s Republic of ChinaCorrespondence: Guiyan Han, Email 1486984873@
Xiao Z +8 more
doaj
Nuclear medicine in endocrine tumours [PDF]
, 2011 C
Peremans, Kathelijne +1 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Common endocrine disorders associated with the polycystic ovary syndrome
Menopause Review, 2021 Ibrahim Abdelazim +2 more
doaj +1 more source