Results 41 to 50 of about 173,464 (288)

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M., Cotinot, C., Evans, N.P., Fowler, P.A., MacDonald, E.S., Mandon-Pepin, B., Rhind, S., Sharpe, R.M.   +7 more
core   +2 more sources

Bisphenol A, phthalate metabolites and glucose homeostasis in healthy normal-weight children

Endocrine Connections, 2018
Introduction: Bisphenol A and several of the most commonly used phthalates have been associated with adverse metabolic health effects such as obesity and diabetes.
Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen, Anders Juul   +4 more
doaj   +1 more source

An integrative method for identification and prioritization of constituents of concern in produced water from onshore oil and gas extraction

Environment International, 2020
In the United States, onshore oil and gas extraction operations generate an estimated 900 billion gallons of produced water annually, making it the largest waste stream associated with upstream development of petroleum hydrocarbons.
Cloelle Danforth, Weihsueh A. Chiu, Ivan Rusyn, Kim Schultz, Ashley Bolden, Carol Kwiatkowski, Elena Craft   +6 more
doaj   +1 more source

Combined exposures to bisphenols, polychlorinated dioxins, paracetamol, and phthalates as drivers of deteriorating semen quality

Environment International, 2022
Background: Semen quality in men continues to decline in Western countries, but the contours of the issue remain obscure, in relation to contributing chemicals.
Andreas Kortenkamp, Martin Scholze, Sibylle Ermler, Lærke Priskorn, Niels Jørgensen, Anna-Maria Andersson, Hanne Frederiksen   +6 more
doaj   +1 more source

The consequences of feminization in breeding groups of wild fish [PDF]

, 2011
EHP is a publication of the U.S. government. Publication of EHP lies in the public domain and is therefore without copyright. Research articles from EHP may be used freely; however, articles from the News section of EHP may contain photographs or ...
Coe, TS, Hamilton, PB, Harris, CA, Henshaw, A, Hodgson, D, Jobling, S, Runnalls, TJ, Sumpter, JP, Tyler, CR, Vinciotti, V   +9 more
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

PFAS health effects database: Protocol for a systematic evidence map

Environment International, 2019
Background: Per- and polyfluoroalkyl substances (PFAS) confer waterproof, greaseproof, and non-stick properties when added to consumer products. They are also used for industrial purposes including in aqueous film forming foams for firefighting. PFAS are
Katherine E. Pelch, Anna Reade, Taylor A.M. Wolffe, Carol F. Kwiatkowski   +3 more
doaj   +1 more source

Evidence suggesting that di-n-butyl phthalate has anti-androgenic effects in fish [PDF]

, 2011
This article is the pre-print version of the full and final published article.Phthalate ester plasticizers are anti-androgenic in mammals. High doses of certain phthalates consistently interfere with the normal development of male offspring exposed in ...
Adams, Akingbemi, Autian, Bjorkblom, Borch, Culty, Dargnat, Filby, Foster, Fromme, Graham, Gray, Han, Harries, Horn, Jobling, Jobling, Jobling, Jolly, Katsiadaki, Katsiadaki, Kim, Lee, Lehmann, Liu, Loraine, Mackintosh, McCurley, Moore, Ogunfowokan, Pfaffl, Schettler, Scott, Scott, Sebire, Shen, Staples, Uren-Webster, Vethaak, Villeneuve   +39 more
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

X‑chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Cell Death and Disease
Klinefelter syndrome (47,XXY) causes infertility with a testicular histology comprising two types of Sertoli cell-only tubules, representing mature and immature-like Sertoli cells, and occasionally focal spermatogenesis.
Sofia B. Winge, Niels E. Skakkebaek, Lise Aksglaede, Gülizar Saritaş, Ewa Rajpert-De Meyts, Ellen Goossens, Anders Juul, Kristian Almstrup   +7 more
doaj   +1 more source