Results 31 to 40 of about 15,308 (249)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Frontiers in Endocrinology, 2021 Crustaceans—and arthropods in general—exhibit many unique aspects to their physiology. These include the requirement to moult (ecdysis) in order to grow and reproduce, the ability to change color, and multiple strategies for sexual differentiation ...
Thomas Knigge +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal
Adsorption Science & Technology, 2005 Porous polysulphone (PSf) microspheres were modified by blending DNA into them and immobilizing DNA onto their surfaces. The DNA-modified microspheres, which were stable in water, were then used to remove endocrine disruptors and heavy metal ions from ...
Changsheng Zhao +6 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Journal of XenobioticsEndocrine disruptors contaminate indoor and outdoor air, water, and food. Besides modifications of the androgen/estrogen balance, endocrine disruptors can alter thyroid function, metabolic balance, immune defenses, and brain development during fetal life,
Charles Sultan +2 more
doaj +1 more source
HYGIENIC ESTIMATION OF THE USE OF PESTICIDES WHICH MAY EXERCITE DISRAPTER OF THE ENDOCRINE SYSTEM
Arta Medica, 2020 Objectives. Pesticides that disrupt the endocrine system are the largest group of endocrine disruptors. Aim of the study was to assess the hygienic estimation of the use of pesticides that affect the endocrine system, applied in the agricultural sector ...
Mariana Zavtoni +3 more
doaj +1 more source
Endocrine disruptors: emerging health concerns
Bangabandhu Sheikh Mujib Medical University Journal, 2023 Abastract not available.
Shahjada Selim
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source