Results 61 to 70 of about 39,893 (289)

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

DNA-Modified Polysulphone Microspheres for Endocrine Disruptors and Heavy Metal Ions Removal

Adsorption Science & Technology, 2005
Porous polysulphone (PSf) microspheres were modified by blending DNA into them and immobilizing DNA onto their surfaces. The DNA-modified microspheres, which were stable in water, were then used to remove endocrine disruptors and heavy metal ions from ...
Changsheng Zhao, Ling Shi, Xingyi Xie, Shudong Sun, Xiangdong Liu, Motoyoshi Nomizu, Norio Nishi   +6 more
doaj   +1 more source

A critical review of the formation of mono- and dicarboxylated metabolic intermediates of alkylphenol polyethoxylates during wastewater treatment and their environmental significance [PDF]

, 2010
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2010 Taylor & Francis.Alkylphenoxyacetic acids, the metabolic biodegradation products of alkylphenol ethoxylates, are commonly found in ...
AEA Technology Environment, Ahel M., Ahel M., Ahel M., APE Research Council, Ashfield L. A., Ball H. A., Barber L. B., Bennie T. D., Bennie T. D., Birkett J. W., Cefic, Cheng C. Y., Comber M. H. I., DiCorcia A., DiCorcia A., DiCorcia A., DiCorcia A., Ding W. H., Ding W. H., Duarte C. L., Dutta A. P., E. Cartmell, Environment Canada and Health Canada, European Commission, European Commission, European Commission, European Commission, Ferguson P. L., Ferguson P. L., Ferguson P. L., Field J. A., Fujii K., Fujita M., Garcia-Reyero N., Gehringer P., Gibson R., Giger W., Giger W., Gray M. A., Gutsche C. D., Haag W. R., Hayashi S., Hill W. J., Hoai P. M., Ike M., Isobe T., Ito Y., J. N. Lester, John D. M., Kinae N., Knepper T. P., Koh Y. K. K., Komori K., Langford K. H., Lee H. B., Lee H. B., Lester J. N., Liu X., M. D. Scrimshaw, Maeda S., Maki H., Maki H., Mann A. H., Mansour M., Manzano M. A., Maruyama K., Mayer T., Minamiyama M., Moraes M. C. F., N. Paterakis, Nguyen M. H., Nimrod A. C., Organisation for Economic Co-operation and Development, Petrovic M., Petrovic M., Petrovic M., Purdom C. E., Reinhard M., Schroder H. F., Servos M. R., Sheahan D., Staples C. A., Stiff M. J., Sumpter J. P., Szymanski A., Szymanski A., T. Y. Chiu, Tanghe T., Tarrant H., Terzic S., Ushida Y., Ventura F., Wagener S., Water Technology International Corporation, Zhang J.   +95 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Effects of Endocrine-Disrupting Chemicals in the Brain: The Example of Neurodevelopment Alterations upon Exposure In Utero to Synthetic Sex Hormones

Journal of Xenobiotics
Endocrine disruptors contaminate indoor and outdoor air, water, and food. Besides modifications of the androgen/estrogen balance, endocrine disruptors can alter thyroid function, metabolic balance, immune defenses, and brain development during fetal life,
Charles Sultan, Laura Gaspari, Marie-Odile Soyer-Gobillard   +2 more
doaj   +1 more source

HYGIENIC ESTIMATION OF THE USE OF PESTICIDES WHICH MAY EXERCITE DISRAPTER OF THE ENDOCRINE SYSTEM

Arta Medica, 2020
Objectives. Pesticides that disrupt the endocrine system are the largest group of endocrine disruptors. Aim of the study was to assess the hygienic estimation of the use of pesticides that affect the endocrine system, applied in the agricultural sector ...
Mariana Zavtoni, Raisa Sîrcu, Ana Volneanschi, Raisa Migalatiev   +3 more
doaj   +1 more source

Endocrine disruptors: emerging health concerns

Bangabandhu Sheikh Mujib Medical University Journal, 2023
Abastract not available.
Shahjada Selim
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exposure to polybrominated diphenyl ethers (PBDEs) suppresses the release of pro-inflammatory products by alveolar macrophages in vitro [PDF]

, 2010
Endocrine disrupting chemicals have adverse effects on immune function that may result in respiratory conditions. Inhalation of dust is a major route of exposure to PBDEs; however, the impact of PBDEs on the immune response is unclear.
Hennigar, Stephen R
core   +1 more source