Results 71 to 80 of about 39,605 (275)
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Introduction: The ecological relevance of chemically induced endocrine disruption in wildlife [PDF]
, 2006 This article is part of the monograph “The Ecological Relevance of Chemically Induced Endocrine Disruption in Wildlife.
Jobling, S, Tyler, CR
core +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]
, 2019 BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes) +9 more
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FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Güncel Pediatri, 2008 Endocrine disruptors are of special interest because they mimic, block, or in some way alter the activity of endogenous chemicals that are synthesized by the endocrine system. Besides many other organs, they especially affect the urinary system and the thyroid glands.
openaire +3 more sources
Frontiers in EndocrinologyObjectiveAlthough radiofrequency ablation (RFA) is a safe and effective non-surgical treatment for benign thyroid nodules, injury to the recurrent laryngeal nerve (RLN), is a potential and feared complication. Intermittent voice checks have been proposed
Marsida Teliti +11 more
doaj +1 more source
Endocrine Disruption by Mixtures in Topical Consumer Products
Cosmetics, 2018 Endocrine disruption has been gathering increasing attention in the past 25 years as a possible new threat for health and safety. Exposure to endocrine disruptor has been progressively linked with a growing number of increasing disease in the human ...
Emiliano Ripamonti +3 more
doaj +1 more source
Can mysid shrimp help us unravel possible endocrine disruption in marine environments? [PDF]
, 2002 Changes in the hormone regulation in animals due to environmental contaminants (endocrine disruptors) has recently become a widely investigated and politically charged issue.
Janssen, C.R., Verslycke, T.
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The Science of Endocrine Disruption - Will It Change the Scope of Products Liability Claims? [PDF]
, 2000 The FDA Food Quality Protection Act of 1996 and amendments to the EPA Safe Drinking Water Act require the EPA Administrator, in consultation with the Secretary of Health and Human Services, to develop a screening program for endocrine disrupting effects.
Fassuliotis, Karen
core +2 more sources