Results 91 to 100 of about 179,235 (348)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

SYNDROME OF MULTIPLE ENDOCRINE NEOPLASIA OF TYPE 1: CLINICAL CASE

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019
Syndrome of multiple endocrine neoplasia of type 1 (MEN type 1, Vermer's syndrome) is a group of heterogeneous hereditary diseases whose pathogenesis is based on hyperplasia or tumoral transformation of several endocrine glands.
Gulinskaya O. V., Prokopchik N. I., Martinkevich O. N.   +2 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

N-Nitrosomorpholine-induced oncocytic transformation in rat endocrine organs

European Journal of Medical Research
Background N-Nitrosomorpholine (NMO) is one of the most common N-nitroso compounds. An oncocytic transformation has been demonstrated in renal tubules of NMO-treated rats.
Emre Gezer, Cüneyt Özer, Turgay Şimşek, Büşra Yaprak Bayrak, Gupse Turan, Berrin Çetinarslan, Alev Selek, Zeynep Cantürk, Mehmet Sözen, Damla Köksalan   +9 more
doaj   +1 more source

Ratiocination of ratios in endocrinology

Journal of the Pakistan Medical Association
Endocrinology is an ever-evolving almanac of science. Precise measurement of hormones and associated analytes are necessary to practice endocrine medicine.
Saptarshi Bhattacharya, Sunetra Mondal, Sanjay Kalra   +2 more
doaj   +1 more source

Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies. [PDF]

Biomedicines, 2023
Radu AM, Carsote M, Nistor C, Dumitrascu MC, Sandru F.   +4 more
europepmc   +1 more source

Persistent isolated hypocortisolism following brief treatment with trilostane [PDF]

, 2008
A 12-year-old male neutered Miniature Poodle with confirmed pituitary-dependent hyperadrenocorticism was treated with trilostane. After three doses, it developed clinical and laboratory changes suggestive of isolated hypocortisolism ('atypical ...
Barker, Bell, Braddock, Chapman, Dunn, Eastwood, Feldman, Hoffman, Javadi, Kintzer, Lifton, Mantis, Neiger, Rao, Ruckstuhl, Russell, Sadek, Sieber-Ruckstuhl, Wenger, Witt   +19 more
core   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Development of a Synthetic Hydrogel to Foster Microvascularization of an Endometriosis Microphysiological System

Advanced Healthcare Materials, EarlyView.
ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett, Laura Bahlmann, Ryan Ogi, Angela Jiao, Priyatanu Roy, Matthew Johnson, David Trumper, Linda Griffith   +7 more
wiley   +1 more source

Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]

, 2016
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M., Cotinot, C., Evans, N.P., Fowler, P.A., MacDonald, E.S., Mandon-Pepin, B., Rhind, S., Sharpe, R.M.   +7 more
core   +2 more sources